摘要
目的 研讨小骨窗经侧裂入路与传统大骨窗手术应用于高血压脑出血(hypertensive intracerebral hemorrhage,HICH)的治疗有效性及安全性。方法 通过方便抽样法,选取2022年3月—2024年3月福建省霞浦县医院确诊为HICH的102例患者为研究对象,根据术式不同分为对照组和观察组,每组51例,对照组接受传统大骨窗手术治疗,观察组接受小骨窗经侧裂入路术治疗,比较两组患者手术基础指标、神经功能、血清炎性指标水平以及并发症发生率。结果 两组患者手术时间比较,差异无统计学意义(P>0.05)。观察组术中出血量少于对照组,住院时间短于对照组,差异有统计学意义(P均<0.05)。术后1个月,观察组神经功能评分低于对照组,差异有统计学意义(P<0.05)。术后1周,观察组3项血清炎性指标(白细胞介素-1β、白细胞介素-6、肿瘤坏死因子-α)水平均低于对照组,差异有统计学意义(P均<0.05)。观察组术后并发症总发生率为5.88%(3/51)低于对照组的19.61%(10/51),差异有统计学意义(χ^(2)=4.319,P=0.037)。结论 与传统大骨窗手术比较,小骨窗经侧裂入路术治疗HICH患者,可缩短患者住院时间,改善患者的神经功能,减轻机体炎性反应,并减少并发症的发生。
Objective To investigate the efficacy and safety of hypertensive intracerebral hemorrhage(HICH) treated by small bone window through lateral fissure approach and traditional large bone window surgery.Methods A total of 102 patients diagnosed with HICH in Xiapu County Hospital of Fujian Province from March 2022 to March 2024 were selected as the study objects by convenient sampling method,and were divided into control group and observation group according to different operation methods,with 51 cases in each group.The control group received traditional surgery with large bone window,and the observation group received lateral fissure approach with small bone window.The basic surgical indexes,nerve function,serum inflammatory indexes and complication rate were compared between the two groups.Results There was no significant difference in operation time between the two groups(P>0.05).The intraoperative blood loss was less than that in the control group,and hospital stay in the observation group was shorter than that in the control group,and the differences were statistically significant(both P<0.05).One month after operation,the neurological function score of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).One week after surgery,the levels of three serum inflammatory indicators(interleukin-1β,interleukin-6,tumor necrosis factor-α) in observation group were lower than those in control group,and the differences were statistically significant(all P<0.05).The total incidence of postoperative complications in the observation group was 5.88%(3/51) lower than that in the control group 19.61%(10/51),the difference was statistically significant(χ^(2)=4.319,P=0.037).Conclusion Compared with traditional large bone window surgery,small bone window though lateral fissure approach can shorten the hospitalization time of HICH patients,improve the neurological function of patients,alleviate the inflammatory response of the body,and reduce the occurrence of com
作者
李晓军
LI Xiaojun(Department of Neurosurgery,Xiapu County Hospital of Fujian Province,Ningde,Fujian,355100,China)
出处
《中外医疗》
2024年第33期48-51,共4页
China & Foreign Medical Treatment
关键词
高血压脑出血
小骨窗经侧裂入路
传统大骨窗手术
神经功能
血清炎性指标
Hypertensive intra cerebral hemorrhage
Small bone window through lateral fissure approach
Traditional large bone window surgery
Neurological function
Serum inflammatory index
