摘要
目的分析梅花针循经叩刺联合桑麻地黄汤对偏头痛患者疼痛、脑血流速度,以及5-羟色胺(5-HT)和内皮素-1(ET-1)水平的影响。方法选择2020年9月至2022年12月该院收治的100例偏头痛患者为研究对象,按照随机数字表法分为观察组与对照组,每组50例。对照组采用桑麻地黄汤治疗,观察组在对照组的基础上采用梅花针循经叩刺治疗,比较两组患者临床疗效、脑血流速度、血清因子水平、疼痛程度[视觉模拟评分法(VAS)]、头痛发作频率、头痛持续时间。结果治疗后,观察组总治疗效率为90.00%,高于对照组的72.00%,差异有统计学意义(P<0.05)。治疗前两组大脑后动脉(PCA)、大脑中动脉(MCA)、大脑前动脉(ACA)平均血流速度,以及VAS评分、头痛发作频率、头痛持续时间、5-HT和ET-1水平比较,差异均无统计学意义(P>0.05)。治疗后,观察组PCA、MCA、ACA平均血流速度,以及VAS评分、头痛发作频率、头痛持续时间、ET-1水平均低于对照组,5-HT水平高于对照组,差异均有统计学意义(P<0.05)。观察组PCA、MCA、ACA平均血流速度,以及VAS评分、头痛发作频率、头痛持续时间、ET-1和5-HT水平治疗前后差值均大于对照组,差异均有统计学意义(P<0.05)。结论梅花针循经叩刺联合桑麻地黄汤可升高偏头痛患者血清5-HT水平,降低ET-1水平,改善患者疼痛等临床症状以及脑血流速度,疗效显著。
Objective To analyze the impacts of pyonex needle tapping along the meridian combined with Sangma Dihuang decoction on pain,cerebral blood flow velocity,and serum levels of 5-hydroxytryptamine(5-HT)and endothelin-1(ET-1)content in migraine patients.Methods A total of 100 migraine patients admitted to Zaozhuang Traditional Chinese Medicine Hospital from September 2020 to December 2022 were collected as the research objects,and were divided into observation group and control group according to the random number table,50 patients in each group.Patients in the control group were treated with Sangma Dihuang Decoction,and patients in the observation group were treated with pyonex needle tapping along the meridians on the basis of the control group.The clinical efficacy,cerebral blood flow velocity,serum factor levels,pain severity[Visual Analog Scale(VAS)],headache frequency and headache duration were compared between the two groups.Results After treatment,the total therapeutic efficiency of the observation group was 90.00%,which was higher than 72.00%of the control group,and the difference was statistically significant(P<0.05).There was no statistically significant difference in the average blood flow velocity of the posterior cerebral artery(PCA),middle cerebral artery(MCA),and anterior cerebral artery(ACA),as well as the VAS score,headache frequency,headache duration,5-HT,and ET-1 levels between the two groups before treatment(P>0.05).After treatment,the average blood flow velocity of PCA,MCA and ACA,as well as VAS score,headache frequency,headache duration,and ET-1 level in the observation group were lower than those in the control group,while 5-HT level was higher than that in the control group,the differences were statistically significant(P<0.05).The average blood flow velocity of PCA,MCA and ACA in the observation group,as well as VAS score,headache frequency,headache duration,and differences in ET-1 and 5-HT levels before and after treatment were greater than those in the control group,the differences were sta
作者
张亮
焦恩虎
ZHANG Liang;JIAO Enhu(The Second Department of Prevention and Treatment,Zaozhuang Traditional Chinese Medicine Hospital,Zaozhuang,Shandong 277000,China)
出处
《检验医学与临床》
CAS
2024年第24期3682-3685,3691,共5页
Laboratory Medicine and Clinic
基金
山东省中医药科技发展计划项目(2019-0644)。
关键词
梅花针循经叩刺
桑麻地黄汤
偏头痛
脑血流速度
5-羟色胺
内皮素-1
pyonex needle tapping along the meridian
Sangma Dihuang decoction
migraine
cerebral blood flow velocity
5-hydroxytryptamine
endothelin-1
