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观察高原地区血清人附睾蛋白4(HE4)和CA125联合检测在卵巢癌患者诊断中的临床应用

Clinical application of combined detection of serum human epididymal protein 4(HE4)and CA125 in the diagnosis of ovarian cancer patients in high-altitude areas
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摘要 目的探析于卵巢癌患者在高原地区进行血清人附睾蛋白4(HE4)和糖类抗原(CA)125联合检测的诊断成效。方法选取2023年1-12月拉萨市人民医院收入的100例疑似卵巢癌患者,均实行HE4和CA125检测,探讨其单一和联合检测的诊断价值。结果在诊断准确率方面,HE4和CA125方法对卵巢癌的诊断价值均高,但两者结合的诊断价值高于单项检测(P<0.05)。结论于在高原地区卵巢癌患者行HE4和CA125联合检测更具检测优势。 Objective To explore the diagnostic effectiveness of combined detection of serum human epididymal protein 4(HE4)and carbohydrate antigen(CA)125 in ovarian cancer patients in high-altitude areas.Methods A total of 100 suspected ovarian cancer patients admitted to Lhasa People's Hospital from January to December 2023 were selected and tested for HE4 and CA125 to explore the diagnostic value of single and combined testing.Results In terms of diagnostic accuracy,both HE4 and CA125 methods have high diagnostic value for ovarian cancer,but the combined diagnostic value of the two is higher than that of single detection(P<0.05).Conclusion The combined detection of serum HE4 and CA125 is more advantageous for ovarian cancer patients in high-altitude areas.
作者 张子玉 庞春兰 陈绪明 景琨 王国洪 ZHANG Ziyu;PANG Chunlan;CHEN Xuming;JING Kun;WANG Guohong(Department of Clinical Laboratory,Lhasa People's Hospital,Lhasa,Tibet 850000,China;Department of Orthopedics,Lhasa People's Hospital,Lhasa,Tibet 850000,China;Department of Clinical Laboratory/Key Laboratory of Malignant Tumor Pathogenesis and Transformation Research,Peking University Cancer Hospital and Beijing Institute of Cancer Prevention and Treatment,Beijing 100142,China)
出处 《国际检验医学杂志》 CAS 2024年第S02期128-130,共3页 International Journal of Laboratory Medicine
关键词 卵巢癌 高原地区 血清人附睾蛋白4 糖类抗原125 联合检测 ovarian cancer high-altitude region serum human epididymal protein 4 carbohydrate antigen 125 combined detection
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