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糠酸莫米松联合功能性鼻内镜手术对慢性鼻窦炎伴鼻息肉患者鼻黏膜纤毛清除率的改善效果

Effect of mometasone furoate combined with functional nasal endoscopic surgery on nasal mucociliary clearance in patients with chronic rhinosinusitis and nasal polyps
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摘要 目的:探讨糠酸莫米松联合功能性鼻内镜手术对慢性鼻窦炎伴鼻息肉患者鼻黏膜纤毛清除率的改善效果。方法:选取2021年1月至2023年12月在张家港市第一人民医院接受治疗的180例慢性鼻窦炎伴鼻息肉患者,采用随机数字表法分组,各90例。常规组采用功能性鼻内镜手术治疗,探究组采用糠酸莫米松联合功能性鼻内镜手术治疗,对比两组疗效。结果:治疗后,两组鼻腔通气功能指标均较治疗前改善,且探究组优于常规组(P<0.05)。治疗后,两组鼻黏膜纤毛清除功能均较治疗前改善,且探究组优于常规组(P<0.05)。探究组术后并发症发生率低于常规组(P<0.05)。结论:糠酸莫米松联合功能性鼻内镜手术治疗慢性鼻窦炎伴鼻息肉效果显著,能改善患者的鼻腔通气功能,提高鼻黏膜纤毛清除率,且能降低术后并发症发生率。 Objective:To investigate the improvement effect of mometasone furoate combined with functional nasal endoscopic surgery on nasal mucosal cilia clearance in patients with chronic rhinosinusitis with nasal polyps.METHODS:One hundred and eighty patients with chronic sinusitis with nasal polyps who were treated in the First Hospital of Zhangjiagang City from January 2021 to December 2023 were selected and grouped into 90 cases each by using the randomized numerical table method.The conventional group was treated with functional nasal endoscopic surgery,and the exploratory group was treated with mometasone furoate combined with functional nasal endoscopic surgery,and the nasal ventilation function,nasal mucosal cilia clearing function,and the incidence of postoperative complications were compared between the two groups.RESULTS:After treatment,the indicators of nasal ventilation function of both groups were improved compared with those before treatment,and the exploratory group was better than the conventional group(P<0.05).After treatment,the nasal mucosal cilia clearance function of both groups improved compared with that before treatment,and the exploratory group was better than the conventional group(P<0.05).The incidence of postoperative complications in the exploratory group was lower than that in the conventional group(P<0.05).CONCLUSION:Mometasone furoate combined with functional nasal endoscopic surgery in the treatment of chronic rhinosinusitis with nasal polyps is effective,which can improve the nasal ventilation function of patients,increase the rate of nasal mucosal cilia clearance,and reduce the incidence of postoperative complications.
作者 徐跃 XU Yue(Department of Otorhinolaryngology,The First People's Hospital of Zhangjiagang,Zhangjiagang 215600,China)
出处 《延边大学医学学报》 CAS 2024年第4期408-410,共3页 Journal of Medical Science Yanbian University
关键词 糠酸莫米松 功能性鼻内镜手术 慢性鼻窦炎 鼻息肉 Mometasone furoate Functional endoscopic sinus surgery Chronic rhinosinusitis Nasal polyps
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