摘要
冠心病是以冠状动脉粥样硬化为病理基础的一类心血管疾病,而中医认为动脉粥样硬化的发生过程与痰、瘀密切相关。现代研究显示,冠心病临床中医证型分类以痰浊、血瘀证居多,痰瘀同治是治疗的关键。因此从中医学痰瘀互结理论探析冠心病的现代医学研究,与现代生物学认识相结合,从血脂、血液流变学、同型半胱氨酸、炎性反应、胰岛素抵抗、相关基因表达差异方面进行基础研究,继而为中药治疗痰瘀互结证冠心病提供临床实践。从中西医结合的视角为冠心病的中医辨证用药提供客观化研究基础,为其预防和治疗增加新的理论依据和诊疗思路。
Coronary heart disease is a kind of cardiovascular diseases based on coronary atherosclerosis,and traditional Chi⁃nese medicine believes that the occurrence process of atherosclerosis is closely related to phlegm and blood stasis.Modern re⁃search shows that the classification of clinical TCM syndrome of coronary heart disease is phlegm and blood stasis,and the treat⁃ment of phlegm and blood stasis is the key to treatment.Therefore,modern medical research on coronary heart disease is explored through the theory of phlegm and blood stasis in traditional Chinese medicine combined with modern biological understanding.Basic research is conducted from the aspects of blood lipids,hemorheology,homocysteine,inflammatory response,insulin resist⁃ance and differences in related gene expression.This provides clinical practice for the traditional Chinese medicine treatment of coronary heart disease with phlegm and blood stasis syndrome.From the perspective of integrated traditional Chinese and western medicine,it provides an objective research basis for TCM syndrome differentiation of coronary heart disease,and adds new theoret⁃ical basis and diagnosis and treatment ideas for its prevention and treatment.
作者
张疆洁
郑娴
ZHANG Jiangjie;ZHENG Xian(Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China;Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110032,Liaoning,China)
出处
《实用中医内科杂志》
2024年第12期132-135,共4页
Journal of Practical Traditional Chinese Internal Medicine
基金
辽宁省自然科学基金项目(2020-MS-227)
辽宁中医药大学自然科学类重点项目(2021LZY053)。
关键词
冠心病
痰瘀互结理论
痰瘀同治
中医治疗
coronary heart disease
phlegm and blood stasis theory
phlegm and blood stasis treatment
traditional Chinese medicine treatment
