摘要
目的比较胎盘绒毛血管参数与脐动脉血流参数在胎儿生长受限(FGR)中的诊断价值。方法收集2020年3月至2023年3月在本院确诊的92例FGR孕妇为观察组,按照1∶1比例收集92例胎儿正常发育孕妇为对照组。测定并比较两组的脐动脉血流参数及胎盘绒毛血管参数,分析FGR发生的影响因素及脐动脉血流参数、胎盘绒毛血管参数对FGR的诊断价值。结果观察组的收缩期峰值血流速度/舒张末期血流速度(S/D)、阻力指数(RI)、搏动指数(PI)高于对照组,胎盘血管化指数(VI)、血管化流量指数(VFI)、血流指数(FI)低于对照组,差异具有统计学意义(P<0.05)。多因素Logistic回归分析结果显示,S/D、RI、PI是FGR发生的危险因素,VI、VFI、FI是保护因素(P<0.05)。受试者工作特征(ROC)曲线结果显示,S/D、RI、PI联合检测的诊断效能优于S/D、RI、PI单一检测(P<0.05);VI、VFI、FI联合检测的诊断效能优于VI、VFI、FI单一检测(P<0.05);胎盘绒毛血管参数联合诊断FGR的效能优于脐动脉血流参数(P<0.05)。结论脐动脉血流参数及胎盘绒毛血管参数异常均与FGR发生密切相关,与脐动脉血流参数联合检测相比,胎盘绒毛血管参数联合检测能更有效地判断FGR发生。
Objective To compare the diagnostic value of placental villus vascular parameters and umbilical artery blood flow parameters in fetal growth restriction(FGR).Methods A total of 92 pregnant women with FGR diagnosed in our hospital from March 2020 to March 2023 were collected as observation group,and 92 pregnant women with normal fetal development were collected as control group according to the ratio of 1∶1.The umbilical artery blood flow parameters and placental villus vascular parameters of the two groups were measured and compared.The influencing factors of FGR and the diagnostic value of umbilical artery blood flow parameters and placental villus vascular parameters for FGR were analyzed.Results The peak systolic velocity/end diastolic velocity(S/D),resistance index(RI)and pulsatility index(PI)in the observation group were higher than those in the control group,and the vascularity index(VI),vascularization flow index(VFI)and flow index(FI)were lower than those in the control group,and the differences were statistically significant(P<0.05).Multivariate Logistic regression analysis showed that S/D,RI and PI were risk factors for FGR,and VI,VFI and FI were protective factors(P<0.05).The results of receiver operating characteristic(ROC)curve showed that the diagnostic efficacy of combined detection of S/D,RI and PI was better than that of single detection of S/D,RI and PI(P<0.05);the diagnostic efficacy of combined detection of VI,VFI and FI was better than that of single detection of VI,VFI and FI(P<0.05);the combination of placental villus vascular parameters was superior to umbilical artery blood flow parameters in the diagnosis of FGR(P<0.05).Conclusion The abnormal umbilical artery blood flow parameters and placental villus vascular parameters are closely related to the occurrence of FGR.Compared with the combined detection of umbilical artery blood flow parameters,the combined detection of placental villus vascular parameters can more effectively determine the occurrence of FGR.
作者
孙素丽
柯珂
李令民
SUN Suli;KE Ke;LI Lingmin(Ultrasonic Diagnosis Center,Xi'an People's Hospital/Xi'an Fourth Hospital,Xi'an 710004,China)
出处
《临床医学研究与实践》
2024年第33期151-154,共4页
Clinical Research and Practice
关键词
胎儿生长受限
胎盘绒毛血管参数
脐动脉血流参数
fetal growth restriction
placental villus vascular parameter
umbilical artery blood flow parameter
