摘要
目的探讨照顾者照顾负担的影响因素及照顾负担与生活质量相关性,为脑深部电刺激术(DBS)后帕金森病患者主要照顾者照顾负担的预防干预提供依据。方法采取横断面研究设计,通过方便抽样法选取2022-01—2023-08南京医科大学附属脑科医院收治85例原发性帕金森病行DBS患者及与患者密切接触时间3个月及以上、年龄≥18岁家庭成员,术前3 d利用社会人口学基本信息调查表收集患者及照顾者基本信息,应用改良Hoehn-Yahr、国际运动障碍协会(MDS)改良统一帕金森病评价量表第Ⅰ、Ⅱ、Ⅲ部分、汉密尔顿焦虑抑郁量表、MMSE、PDQ39、蒙特利尔认知评估、神经精神科问卷(NPI)对患者进行调查,分析患者疾病状态。术前24 h,应用照顾者负担量表(ZBI)、照顾相关生活质量(CarerQol)量表对照顾者进行调查,通过Spearman等级相关分析,进行照顾者负担相关影响因素分析,探讨脑深部电刺激术后帕金森病患者照顾者负担影响因素及与生活质量相关性。结果患者片段化睡眠达69.4%,PDQ39平均(47.31±20.15),自理能力部分需要帮助72.9%,精神行为除妄想外余9条均与照顾者负担呈正相关(P<0.05)。照顾者ZBI得分(46.99±18.97),其中无负担占8.2%,轻度占29.4%,中度占32.9%,重度占29.4%。CarerQol-7D得分6.92±3.20,CarerQol-VAS得分4.84±2.34,且ZBI与CarerQol-7D除成就感外其他6项及总分均呈正相关,P<0.05。结论脑深部电刺激术后帕金森病患者照顾者普遍存在照顾负担,并影响其生活质量,影响因素较多,其中苦恼程度、情绪状态、生活自理程度、照顾者与患者亲密关系是照顾者负担重要独立影响因素,临床医务人员需重视并予以措施,以减轻这类人群照顾负担,提高其及患者生活质量。
Objective To investigate the factors influencing caregiver burden and its correlation with(quality of life PD)patients undergoing deep brain stimulation,providing a basis for preventive interventions for the primary caregivers of Parkinson(DBS).Methods’s disease A cross-sectional study was conducted from January 2022 to August 2023,involving 85 primary PD patients treated by DBS at Nanjing Medical University Affiliated Brain Hospital,and their family members who had been in close contact with the patients for at least 3 months and were aged≥18 years.Three days prior to the surgery,demographic information of patients and caregivers was gathered through the use of a socio-demographic questionnaire.Patients underwent assessment using the modified Hoehn-Yahr scale,modified unified Parkinson’s disease evaluation scale(MDS),PartsⅠ,Ⅱ,Ⅲ,Hamilton anxiety and depression scale,MMSE,PDQ39,Montreal cognitive assessment,and neuropsychiatric questionnaire(NPI)to evaluate their disease status.Twenty-four hours before the surgery,carer burden scale(ZBI)and carer related quality of life(Carer Qol)were utilized to assess caregivers.Spearman correlation analysis was employed to examine factors influencing caregiver burden and its association with quality of life in Parkinson’s disease patients following deep brain stimulation.Results Fragmented sleep in patients was 69.4%,with an average PDQ-39 score of 47.31±20.15.Partial self-care assistance was required by 72.9%of patients.Except for delusions,the other nine items of mental behavior were positively correlated with caregiver burden(P<0.05).The average caregiver ZBI score was 46.99±18.97,with 8.2%reporting no burden,29.4%reporting mild burden,32.9%reporting moderate burden,and 29.4%reporting severe burden.Carer Qol-7D scored 6.92±3.20,and Carer Qol-VAS scored 4.84±2.34.ZBI scores were positively correlated with Carer Qol-7D,except for the sense of accomplishment(P<0.05).Conclusion Caregivers of PD patients post-DBS commonly experience care burden,which affects the
作者
曹峰
王红
吴佳乐
张燕红
章文斌
王晓
胡昕怡
CAO Feng;WANG Hong;WU Jiale;ZHANG Yanhong;ZHANG Wenbin;WANG Xiao;HU Xinyi(The Affiliated Brain Hospital of Nanjing Medical University,Nanjing 210029,China)
出处
《中国实用神经疾病杂志》
2024年第11期1419-1424,共6页
Chinese Journal of Practical Nervous Diseases
基金
江苏省重点研发计划专项资金项目(编号:BE2022049,BE2022049-1)。
关键词
帕金森病
脑深部电刺激术
照顾者
照顾负担
影响因素
生活质量
Parkinson’s disease
Deep brain stimulation
Caregiver
Care burden
Influencing factors
Quality of life
