摘要
目的:探究去乙酰毛花苷联合盐酸胺碘酮应用于急诊抢救心力衰竭伴快速心房颤动患者的效果。方法:选择2023年1—12月松原市中心医院收治的84例心力衰竭伴快速心房颤动患者为研究对象,按奇偶数法将其分为对照组和研究组,各42例。对照组采用去乙酰毛花苷治疗,研究组在对照组基础上联合盐酸胺碘酮治疗。对比两组治疗总有效率、不良反应发生情况、心功能指标、心肌细胞损伤指标及炎症指标。结果:治疗后,研究组治疗总有效率为95.24%,高于对照组的80.95%,差异有统计学意义(P<0.05)。治疗后,研究组心排血量、左心室射血分数、每搏输出量均高于对照组,差异均有统计学意义(P<0.05)。治疗后,研究组N末端B型钠尿肽前体、高敏心肌肌钙蛋白T、肌酸激酶同工酶、乳酸脱氢酶含量水平均低于对照组,差异均有统计学意义(P<0.05)。治疗后,研究组超敏C反应蛋白、白细胞介素-6均低于对照组,差异均有统计学意义(P<0.05)。治疗后,研究组不良反应发生率为7.14%,相较于对照组的4.76%,差异无统计学意义(P>0.05)。结论:去乙酰毛花苷联合盐酸胺碘酮应用于急诊抢救心力衰竭伴快速心房颤动患者,用药疗效显著且安全性高,可有效促进患者心功能恢复,减轻心肌细胞损伤并促进炎症消退。
Objective:To explore the effect of Deslanoside combined with Amiodarone Hydrochloride in emergency treatment of patients with heart failure and rapid atrial fibrillation.Methods:A total of 84 patients with heart failure and rapid atrial fibrillation admitted to Songyuan Central Hospital from January to December 2023 were selected as the study objects.They were divided into a control group and a study group according to odd and even number method,with 42 cases in each group.The control group was treated with Deslanoside,the study group was treated with Amiodarone Hydrochloride on basis of the control group.The total effective rate,occurrence of adverse reactions,cardiac function indexes,myocardial cell injury indexes and inflammatory indexes were compared between the two groups.Results:After treatment,the total effective rate of the study group was 95.24%,which was higher than 80.95%of the control group,the difference was statistically significant(P<0.05).After treatment,cardiac output,left ventricular ejection fraction and stroke output in the study group were higher than those in the control group,with statistical significance(P<0.05).After treatment,the contents of N-terminal B-type natriuretic peptide precursor,high-sensitive cardiac troponin T,creatine kinase isoenzyme and lactate dehydrogenase in the study group were lower than those in the control group,with statistical significance(P<0.05).After treatment,hypersensitive C-reactive protein and interleukin-6 in the study group were lower than those in the control group,the differences were statistically significant(P<0.05).After treatment,the incidence of adverse reactions in the study group was 7.14%,compared with 4.76%in the control group,with no statistical significance(P>0.05).Conclusion:The application of Deslanoside combined with Amiodarone Hydrochloride in emergency treatment of patients with heart failure and rapid atrial fibrillation has significant efficacy and high safety,which can effectively promote the recovery of cardiac function,alleviating m
作者
张春风
ZHANG Chunfeng(Department of Emergency,Songyuan Central Hospital,Songyuan 138000,China)
出处
《中国伤残医学》
2024年第14期37-41,共5页
Chinese Journal of Trauma and Disability Medicine
关键词
心力衰竭
快速心房颤动
去乙酰毛花苷
盐酸胺碘酮
不良反应
心功能
Heart failure
Rapid atrial fibrillation
Deslanoside
Amiodarone Hydrochloride
Adverse reactions
Cardiac function
