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全身麻醉下Ⅰ型甲状软骨成形术治疗单侧声带麻痹远期疗效观察

Long-term efficacy of typeⅠthyroplasty under general anesthesia in the treatment of unilateral vocal cord paralysis
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摘要 目的观察全身麻醉下Ⅰ型甲状软骨成形术治疗单侧声带麻痹所致声门关闭不全的远期效果。方法对2017年1月~2023年6月就诊于北京同仁医院并于全麻下接受Ⅰ型甲状软骨成形术治疗的52例单侧声带麻痹患者进行1年以上长期随访,分析其嗓音学参数变化。结果52例患者均在全身麻醉下顺利完成手术,术后声嘶均改善,饮水呛咳消失,患侧声带内移,声门闭合改善。术后1年患侧声带位置较术后1周无明显变化。所有患者术前、术后1周、术后1年的嗓音障碍视觉模拟量表(VAS)评分依次减小(80.28±13.49 vs.37.78±19.15 vs.26.26±21.29,P<0.05),术前及术后1年的嗓音主观听感知评估(GRBAS)除发音过度紧张程度(S)外,总嘶哑度(G)、粗糙声程度(R)、气息声程度(B)及发音无力程度(A)评分差异均有统计学意义(2.70±0.47 vs.1.09±0.66、2.52±0.54 vs.0.85±0.67、2.85±0.36 vs.0.67±0.65、2.74±0.44 vs.0.61±0.80,P均<0.05);与术前相比,术后1年基频(F0)和振幅微扰(shimmer)明显下降(4.61±2.61 vs.3.05±2.37、9.52±3.91 vs.7.11±2.78,P<0.05),最长发声时间(maximum phonation time,MPT)明显延长(5.87±2.70 vs.14.50±4.30,P<0.05)。无患者出现围术期不良事件。结论Ⅰ型甲状软骨成形术是治疗单侧声带麻痹的外科有效手段,全身麻醉下进行该手术,患者手术时没有痛苦、安全,而且能够达到显著改善患者声音嘶哑症状的治疗效果,疗效稳定、持久。 OBJECTIVE To observe the long-term efficacy of type-Ⅰthyroplasty under general anesthesia in the treatment of glottal insufficiency caused by unilateral vocal cord paralysis.METHODS A total of 52 patients with unilateral vocal cord paralysis who underwent type-Ⅰthyroplasty under general anesthesia at Beijing Tongren Hospital from January 2017 to June 2023 were followed up for more than one year to analyze their efficacy.RESULTS All 52 patients underwent surgery successfully under general anesthesia,and hoarseness improved after operation.Coughing caused by drinking water was reduced or disappeared,and the vocal cords moved inward with improved glottal closure.One year after operation,there was no significant change in the position of the affected vocal cords compared to one week after surgery.The visual analog scale(VAS)scores of all patients with voice disorders decreased sequentially before surgery,one week after surgery,and one year after surgery(80.28±13.49 vs.37.78±19.15 vs.26.26±21.29,P<0.05).The preoperative and one-year postoperative voice perception assessment(GRBAS)showed statistically differences in grade(G),rough(R),breathy(B),and asthenia(A)scores(2.70±0.47 vs.1.09±0.66,2.52±0.54 vs.0.85±0.67,2.85±0.36 vs.0.67±0.65,2.74±0.44 vs.0.61±0.80,P<0.05)except for strain(S).Compared with preoperative results,one-year postoperatively showed a significant decrease in jitter and shimmer(4.61±2.61 vs.3.05±2.37,9.52±3.91 vs.7.11±2.78,P<0.05),and a significant prolongation of maximum phonation time(MPT)[(5.87±2.70)s vs.(14.50±4.30)s,P<0.05].No patients experienced perioperative adverse events.CONCLUSION Type-Ⅰthyroplasty is an effective surgical method for treatment of vocal cord paralysis.The type-Ⅰthyroplasty under general anesthesia is safe and effective,which not only significantly improves the symptoms of hoarseness in patients,but also has stable therapeutic effects and can maintain the results for a long time.At the same time,the patient has no pain during the procedure.
作者 石军 肖洋 王军 奚春花 宋佳露 马丽晶 SHI Jun;XIAO Yang;WANG Jun;XI Chunhua;SONG Jialu;MA Lijing(Department of Anesthesiology,Beijing Tongren Hospital,Capital Medical University,Key Laboratory of Otolaryngology Head and Neck Surgery(Capital Medical University),Ministry of Education,Beijing,100730,China;Department of Otolaryngology Head and Neck Surgery,Beijing Tongren Hospital,Capital Medical University,Key Laboratory of Otolaryngology Head and Neck Surgery(Capital Medical University),Ministry of Education,Beijing,100730,China)
出处 《中国耳鼻咽喉头颈外科》 CSCD 2024年第10期657-660,共4页 Chinese Archives of Otolaryngology-Head and Neck Surgery
基金 北京市医院管理中心儿科学科协同发展中心专项经费(XTCX201823) 北京市中医药科技发展资金项目(JJ-2020-17) 北京市属医院科研培育计划(PX2023008)。
关键词 麻醉 全身 声带麻痹 治疗结果 甲状软骨成形术 Anesthesia,General Vocal Cord Paralysis Treatment Outcome type-1 thyroplasty
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