摘要
茵陈为肝胆系疾病常用中药,是经典利湿退黄药,具有清热利湿、利胆退黄的功效,其主要化学成分包括黄酮类、香豆素类、有机酸类、挥发油类化合物等;现代药理研究表明其具有抗炎、抗氧化、抗病毒、抗癌、抗糖尿病及代谢综合征等作用,临床上主治黄疸尿少、湿温暑湿、湿疮瘙痒,治疗疟疾、肝炎、胆石症、胆囊炎、肝癌等疾病。对茵陈中的化学成分、药理作用机制、在肝胆系疾病的临床应用进行全面总结及分析,以期为茵陈的进一步开发和利用提供参考。
Yinchen(Artemisiae Scopariae Herba)is a traditional Chinese medicine commonly used for hepatobiliary diseases,and it is a classic medicine for promoting diuresis and eliminating jaundice.Its main chemical components include flavonoids,coumarins,organic acids,volatile oil compounds,etc.Modern pharmacological research shows that it has anti-inflammatory,anti-oxidation,anti-virus,anti-cancer,anti-diabetes and metabolic syndrome effects,and is mainly used for treating jaundice,oliguria,damp-heat and summer-dampness,wet sores and itching,malaria,hepatitis,cholelithiasis,cholecystitis,liver cancer and so on.This paper reviewed its chemical constituents,pharmacological mechanism and clinical application of Yinchen(Artemisiae Scopariae Herba)in hepatobiliary diseases were comprehensively summarized and analyzed in order to provide reference for the further development and utilization of Artemisiae Scopariae Herba.
作者
闫雅婕
王亚亚
梁轩
王安婧
苏静
李彩东
YAN Yajie;WANG Yaya;LIANG Xuan;WANG Anjing;SU Jing;LI Caidong(Gansu University of Chinese Medicine,Lanzhou 730000,Gansu,China;The Second People’s Hospital of Lanzhou,Lanzhou 730000,Gansu,China;Nanjing Agricultural University,Nanjing 210095,Jiangsu,China)
出处
《中华中医药学刊》
CAS
北大核心
2024年第11期237-248,共12页
Chinese Archives of Traditional Chinese Medicine
基金
甘肃省药品监督管理局科研项目(2023 GSMPA021)
兰州市卫生健康行业科研项目(A2023015)
兰州市科技计划项目(2023-4-16)。
关键词
茵陈
化学成分
药理活性
临床应用
肝胆疾病
Yinchen(Artemisiae Scopariae Herba)
chemical composition
pharmacological activity
clinical application
hepatobiliary diseases
