摘要
通过查阅相关古籍和现代文献记载,对黄精的历史炮制沿革,现代黄精炮制工艺,炮制后化学成分变化和药理作用进行整理汇总,可为黄精炮制品的规范发展提供依据。通过古籍记载,黄精的炮制方法有生品晒制、黄酒煎制、生品九蒸九制、黄酒蒸制、黑豆熬制、蜜制等,酒制记载最多且分类详细,沿用至今的有酒制法、蜜制法等炮制品。现代炮制方法大都为直接切片、九蒸九制等炮制方法,方法较为统一,目前文献记载黄酒炮制后发生变化的化学成分有多糖、皂苷、黄酮等,黄精炮制品的药理作用有抗氧化、抗肿瘤、抗炎、抗菌、抗病毒等,但炮制药理研究中缺乏含量变化与药理作用的相关性研究。此后研究可基于黄精炮制工艺与成分含量变化机理的分析,进一步探索成分变化与药理作用之间的关系,阐明黄精炮制的成分变化的分子机制,为后续黄精炮制饮片的标准和药理应用奠定基础。
By consulting related ancient books and modern literature,the historical processing evolution,modern processing technology,chemical composition changes and pharmacological effects of Huangjing(Polygonati Rhizoma)were summarized,which can provide the basis for the standardized development of Huangjing(Polygonati Rhizoma)processed products.According to ancient records,the processing methods of Huangjing(Polygonati Rhizoma)include raw product sun processing,yellow wine processing,raw nine-steaming nine-steaming,yellow wine steaming,black bean boiling,honey processing,etc.The wine processing has the most records and detailed classification,and there are wine processing,honey processing and other processed products that are still in use today.Modern processing methods are mostly direct slicing,nine-steaming and nine-processing,and the methods are relatively unified.At present,it is recorded in the literature that the chemical components of yellow rice wine after processing are polysaccharides,saponins,flavonoids,etc.,and the pharmacological effects of processed Huangjing(Polygonati Rhizoma)products are antioxidant,anti-tumor,anti-inflammatory,antibacterial and antiviral,etc.,but there is a lack of correlation between content changes and pharmacological effects in the processing pharmacological research.After that,based on the analysis of the processing technology of Huangjing(Polygonati Rhizoma)and the change mechanism of component content,it can further explore the relationship between component change and pharmacological action,clarify the molecular mechanism of component change of Huangjing(Polygonati Rhizoma)and lay the foundation for the standard and pharmacological application of Huangjing(Polygonati Rhizoma)processed pieces.
作者
陈小磊
徐哲
钱华丽
董家红
张磊
季鹏章
CHEN Xiaolei;XU Zhe;QIAN Huali;DONG Jiahong;ZHANG Lei;JI Pengzhang(Institute of Medicinal Plant Cultivation,Academy of Southern Medicine,Yunnan University of Chinese Medicine,Kunming 650500,Yunnan,China)
出处
《中华中医药学刊》
CAS
北大核心
2024年第11期150-157,共8页
Chinese Archives of Traditional Chinese Medicine
基金
国家自然科学基金项目(31760347)
中央引导地方科技发展基金项目(202307AB110002)
云南省科技厅-云南中医药大学中医联合专项重点项目(202001 AZ070001-010)。
关键词
黄精
炮制
成分变化
药理
Huangjing(Polygonati Rhizoma)
processing
composition changes
pharmacology
