摘要
目的:探究超声引导下经皮肝穿刺胆管引流术(PTCD)对阻塞性黄疸的影响。方法:回顾性选取2020年1月—2023年12月三明市第一医院收治的92例阻塞性黄疸患者作为研究对象。根据不同手术方式将其分为对照组(n=46)和研究组(n=46)。对照组采用解剖性左半肝切除术,研究组采用超声引导下的PTCD。比较两组围手术期指标,术前及术后胆红素指标、肝功能指标、免疫功能及并发症。结果:研究组手术时间、住院时间均短于对照组,首次下床活动时间早于对照组,胆汁引流量和术中出血量均少于对照组,差异有统计学意义(P<0.05)。术后,两组总胆红素(TBIL)、直接胆红素(DBIL)和间接胆红素(IBIL)水平均降低,研究组TBIL、DBIL、IBIL水平均低于对照组,差异有统计学意义(P<0.05)。术后,两组丙氨酸氨基转移酶(ALT)、碱性磷酸酶(ALP)、γ-谷氨酰基转移酶(GGT)、天门冬氨酸氨基转移酶(AST)水平均降低,研究组ALT、ALP、GGT、AST水平均低于对照组,差异有统计学意义(P<0.05)。术后,两组免疫球蛋白A(IgA)、免疫球蛋白G(IgG)、免疫球蛋白M(IgM)水平均降低,研究组IgA、IgG、IgM水平均高于对照组,差异有统计学意义(P<0.05)。术后,研究组并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论:超声引导下PTCD能够加速患者恢复,减轻黄疸程度,改善肝功能,加速免疫功能恢复,降低并发症发生率。
Objective:To explore the effect of ultrasound-guided percutaneous transhepatic biliary drainage(PTCD)on obstructive jaundice.Method:A total of 92 patients with obstructive jaundice admitted to the Sanming First Hospital from January 2020 to December 2023 were retrospectively selected as the study objects.They were divided into control group(n=46)and study group(n=46)according to different surgical methods.The control group underwent anatomic left hemihepatectomy,and the study group underwent ultrasound-guided PTCD.Perioperative indexes,preoperative and postoperative bilirubin indexes,liver function indexes,immune function and complications were compared between the two groups.Result:The operation time and hospital stay of the study group were shorter than those of the control group,the first time of getting out of bed was earlier than that of the control group,and the bile drainage volume and intraoperative blood loss were less than those of the control group,the differences were statistically significant(P<0.05).After surgery,the levels of total bilirubin(TBIL),direct bilirubin(DBIL)and indirect bilirubin(IBIL)were decreased in both groups,and the levels of TBIL,DBIL and IBIL in the study group were lower than those in the control group,the differences were statistically significant(P<0.05).After surgery,the levels of alanine aminotransferase(ALT),alkaline phosphatase(ALP),γ-glutamyltransferase(GGT)and aspartate aminotransferase(AST)in both groups were decreased,and the levels of ALT,ALP,GGT and AST in the study group were lower than those in the control group,the differences were statistically significant(P<0.05).After surgery,the levels of immunoglobulin A(IgA),immunoglobulin G(IgG)and immunoglobulin M(IgM)were decreased in both groups,and the levels of IgA,IgG and IgM in the study group were higher than those in the control group,the differen ces were statistically significant(P<0.05).After surgery,the incidence of complication of the study group was lower than that of the control group,the difference was st
作者
吴光华
廖春旭
李旭巍
林志高
WU Guanghua;LIAO Chunxu;LI Xuwei;LIN Zhigao(Sanming First Hospital,Sanming 365000,China;不详)
出处
《中外医学研究》
2024年第31期21-26,共6页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
超声引导
经皮肝穿刺胆管引流术
阻塞性黄疸
Ultrasound guidance
Percutaneous transhepatic biliary drainage
Obstructive jaundice
