摘要
目的分析缺血性肠病患者行康复新液联合静脉滴注罂粟碱治疗的效果。方法选取2020年1月—2023年10月南通苏通科技产业园区江海医院收治的70例缺血性肠病患者为研究对象,按治疗方法不同分成观察组(康复新液+罂粟碱治疗)、对照组(康复新液治疗),各35例。比较两组治疗总有效率、病症改善时间、炎症因子水平、D-二聚体水平以及不良反应发生情况。结果观察组治疗总有效率97.14%(34/35),显著高于对照组80.00%(28/35),差异有统计学意义(χ^(2)=5.081,P<0.05)。观察组腹痛缓解时间、大便隐血转阴时间、肠道出血消失时间、功能恢复时间及住院时间均短于对照组,差异有统计学意义(P均<0.05)。治疗前,两组血清炎症因子水平、D-二聚体水平比较,差异无统计学意义(P均>0.05)。治疗后,观察组C反应蛋白、白细胞介素-6、D-二聚体水平均低于对照组,差异有统计学意义(P均<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论缺血性肠病患者行康复新液联合静脉滴注罂粟碱治疗可以加快病症的缓解速度,并明显减轻机体炎症反应,还能够降低D-二聚体水平,且不存在加重不良反应的问题。
Objective To analyze the effect Kangfuxin Liquid Combined with of intravenous infusion of Kangfuxin Liquid Combined with papaverine on patients with ischemic bowel disease.Methods A total of 70 patients with ischemic bowel disease admitted to Nantong Sutong Science and Technology Industrial Park Jianghai Hospital from January 2020 to October 2023 were selected as the study objects.According to different treatment methods,they were divided into observation group(Kangfuxin Liquid+papaverine treatment)and control group(Kangfuxin Liquid treatment),with 35 cases in each group.The total effective rate of treatment,symptoms improvement time,inflammatory factor levels,D-dimer levels and adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 97.14%(34/35),which was significantly higher than 80.00%(28/35)of the control group,and the difference was statistically significant(χ^(2)=5.081,P<0.05).The time of abdominal pain relief,the time of fecal occult blood turning negative,the time of intestinal bleeding disappearance,the time of functional recovery and the time of hospitalization in the observation group were shorter than those in the control group,and the differences were statistically significant(all P<0.05).Before treatment,there was no significant difference in the levels of serum inflammatory factors and Ddimer between the two groups(both P>0.05).After treatment,the levels of C-reactive protein,interleukin-6 and D-dimer in the observation group were lower than those in the control group,and the differences were statistically significant(both P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Kangfuxin Liquid Combined with Intravenous infusion of papaverine can accelerate the remission rate of ischemic bowel disease in patients,significantly reduce the body's inflammatory response and D-dimer levels.And there is no problem of exacerbating adverse reactions.
作者
何秀银
HE Xiuyin(Department of Internal Medicine,Nantong Sutong Science and Technology Industrial Park Jianghai Hospital,Nantong 226000,Jiangsu,China)
出处
《世界复合医学（中英文）》
2024年第8期61-64,共4页
World Journal of Complex Medicine
关键词
缺血性肠病
静脉滴注罂粟碱
病情康复速度
炎症因子
D-二聚体
Ischemic bowel disease
Intravenous infusion of papaverine
Speed of recovery from illness
Inflammatory factors
D-dimer
