摘要
富血小板血浆(platelet-rich plasma,PRP),是利用患者的全血通过离心过程获得的富含血小板的生物制品,其血小板浓度可以达到正常值的3~6倍。PRP的使用旨在通过将受损组织暴露于高浓度的自体生长因子来增强其自我修复能力^([1-2]),因为血小板中含有丰富的生长因子和细胞因子,其在激活时活化从而释放出这些物质,起到减轻炎症反应、调节代谢、促进细胞增殖和基质形成的作用。
Platelet-rich plasma(PRP)is an autologous platelet concentrate prepared from the whole blood.PRP is rich in growth factors(GFs)and cytokines,which play roles in anti-inflammatory,tissue healing,and matrix formation.It has been widely used in orthopedics.The efficacy of PRP in carpal tunnel syndrome,lateral epicondylitis,tenosynovitis,tendinopathy,osteoarthritis,and fracture has been affirmed.PRP can achieve similar or even better treatment effects than traditional treatment,especially for symptom relief and functional improvement.This literature reviewed the clinical applications of PRP in hand surgery at home and abroad in recent years to provide references for surgeons and clinical scholars.However,due to the differences in the PRP concentration and components used by scholars,the results were different,which also suggested the necessity of standardized concentration,components,and application of PRP.Despite many problems in the current studies about PRP,further studies are needed.
作者
李洪晓
伊喆
李文军
LI Hong-xiao;YI Zhe;LI Wen-jun(Beijing Jishuitan Hospital,Capital Medical University,Beijing,100035,China)
出处
《中国骨与关节杂志》
CAS
2024年第10期809-813,共5页
Chinese Journal of Bone and Joint
基金
北京市自然科学基金-海淀原始创新联合项目(L212043)
北京市医院管理中心“登峰”计划(DFL20240402)。
关键词
富血小板血浆
腕管综合征
肱骨
骨关节炎
网球肘
综述
Platelet-rich plasma
Carpal tunnel syndrome
Humerus
Osteoarthritis
Tennis elbow
Review
