摘要
目的基于国内外公开发表的中药药物警戒为主题的期刊文献,构建中药药物警戒研究知识图谱,探讨其研究热点及发展方向。方法在中国知网、Web of science数据库检索近10年来国内外以“中药药物警戒”为主题的学术研究机构发表的相关文献,利用CiteSpace软件对其作者分布、关键词共现、关键词聚类、关键词突现等进行知识图谱分析。结果共纳入2785篇中文文献和229篇英文文献,主要突显出3个研究团队与研究机构。研究范畴主要集中于中药不良反应的识别、中药毒性机制的理解、中药风险防范与合理用药转化3个方面,研究内容不断深入、丰富。国内外发文热点各有侧重,对中药注射剂等安全问题关注持久。结合研究现状与未来发展思考,建立中药药物警戒发展与研究思维导图。结论中药药物警戒的建设应在传承中医药传统的同时,创新发挥现代技术优势,示范引领国际植物药药物警戒发展。
Objective To construct a knowledge graph for pharmacovigilance research in traditional Chinese medicine(TCM)by analyzing publicly published journal literature from both domestic and international sources,which is to identify research hotspots and future development directions in the field.Methods Relevant literatures published by academic and research institutions on“pharmacovigilance of TCM”published during the previous decade was searched using the National Knowledge Infrastructure of China and Web of Science databases.The knowledge graph was analyzed using CiteSpace software to explore author distribution,keyword co-occurrence,keywords clustering,and keywords burst.Results Three primary research teams and institutions were highlighted in a total of 2785 Chinese and 229 English articles.The three main areas of research concentration were risk avoidance,rational medication,identification of adverse reactions to TCM,and understanding the processes of TCM toxicity.The study material had consistently been expanded and improved.Hotspots for publications,both domestically and internationally,have distinct focuses.There had been a continuous emphasis on safety concerns related to injections used in TCM.A mental map of TCM pharmacovigilance research and development was created by integrating the current knowledge of the field with future development prospects.Conclusion To establish pharmacovigilance,it is essential to honor the principles of TCM,while effectively utilizing modern technology,which will also contribute to the advancement of international pharmacovigilance of botanical medicines.
作者
张晓朦
贺鑫
杨莹
张冰
林志健
ZHANG Xiaomeng;HE Xin;YANG Ying;ZHANG Bing;LIN Zhijian(School of Chinese Materia Medica,Beijing University of Chinese Medicine,Beijing 102488,China;Center for Pharmacovigilance of Chinese Materia Medica Research,Beijing University of Chinese Medicine,Beijing 102488,China)
出处
《中国药物警戒》
2024年第10期1118-1124,共7页
Chinese Journal of Pharmacovigilance
基金
国家自然科学基金资助项目(82204643、82274117)。
关键词
中药
药物警戒
知识图谱
思维导图
中药注射剂
traditional Chinese medicine
pharmacovigilance
knowledge graphs analysis
mental map
TCM injections
