摘要
目的:对比结肠癌患者接受单孔加一腹腔镜手术(Single-Incision Plus One Port Laparoscopic Surgery,SILS+1)与常规5孔腹腔镜手术的治疗效果。方法:收集2021年3月~2022年2月在本院胃肠外科接受结肠癌根治术患者为研究对象,根据手术方式将其分为观察组(接受SILS+1,n=53)和对照组(接受5孔腹腔镜手术,n=55);首先分析比较两种手术方法围手术期指标和实验室如白蛋白、总蛋白、C-反应蛋白(C-reactive protein,CRP)等;再比较两组术后数字疼痛强度量表(numerical rating scale,NRS)评分,并发症和随访结果。结果:两组术中出血量、淋巴结清扫数量和pTNM分期、首次进食时间无差异(P>0.05);接受SILS+1患者首次下床、排气、住院时间均低于对照组,手术时间长于对照组(P<0.05);两组患者术前总蛋白、白蛋白、去甲肾上腺素(Norepinephrine,NE)、CRP、白细胞介素-6(Interleukin-6,IL-6)水平无差异(P>0.05),术后总蛋白、白蛋白较术前下降,CRP、IL-6、NE较术前升高(P<0.05),组间差异显著(P<0.05);术后第12、24、48h的NRS评分,观察组均低于对照组(P<0.05);观察组和对照组并发症发生率(3.77%,5.45%)、2年总生存率(94.33%,92.72%)和复发率(21.56%,23.63%),相比无统计学差异(P>0.05)。结论:与常规5孔腹腔镜手术相比,SILS+1在结肠癌根治术中具备术后康复快、痛感低、炎症反应轻和住院时间短等优势,长期疗效与传统腹腔镜手术(CLS)相比无差异。
Objective:To compare the treatment outcomes of colon cancer patients undergoing single-incision plus one port laparoscopic surgery(SILS+1)or conventional fiveport laparoscopic surgery.Methods:The colon cancer patients admitted in Department of Gastrointestinal Surgery in our hospital for radical surgery from March 2021 to February 2022 were selected as subjects.Patients were divided into an observation group(receiving SILS+1,n=53)and a control group(conventional fiveport laparoscopic surgery,n=55).Comparison of perioperative indicators and laboratory values such as albumin,total protein,and C-reactive protein(CRP)were conducted between two groups.Postoperative pain was assessed and compared via numerical rating scale(NRS),complications and follow-up results were also compared.Results:There were no significant differences between the two groups in terms of intraoperative blood loss,lymph node dissection counts,pTNM staging,and initial postoperative feeding time(P>0.05).The first time of getting off bed,expelling flatus,defecation and hospital stay in patients treated with SILS+1 were all shorter than those of the control group,but surgery times was longer in observation group(P<0.05).Preoperative levels of total protein,albumin,norepinephrine(NE),CRP,and interleukin-6(IL-6)were of no statistic difference between two groups(P>0.05).Postoperatively,total protein and albumin levels decreased,while CRP,IL-6,and NE increased in both groups(P<0.05),all above indicators show significant differences between groups(P>0.05).Postoperative NRS scores at 12,24,and 48 hours were lower in the observation group(P<0.05).The incidence of complications(3.77%,5.45%),2-year overall survival rates(94.33%,92.72%)and 2-year recurrence rates(21.56%,23.63%)were similar between two groups(P>0.05).Conclusion:Compared to conventional five-port laparoscopic surgery,SILS+1 in radical colon cancer surgery exhibited advantages such as faster postoperative recovery,less pain,milder inflammatory responses,and shorter hospital stays.Long-term therap
作者
李风臣
刘延军
王海波
LI Feng-chen;LIU Yan-jun;WANG Hai-bo(Gastrointestinal Surgery Department,the 970th Hospital of the PLA Joint Logistic Support Force,Shandong Yantai 264000)
出处
《中国医疗器械信息》
2024年第20期7-10,共4页
China Medical Device Information
关键词
传统腹腔镜手术
单孔加一腹腔镜手术
结肠癌根治术
数字疼痛强度量表
总蛋白
conventional laparoscopic surgery
single-incision plus one laparoscopic surgery
radical surgery for colon cancer
numerical rating scale
total protein
