摘要
目的探讨早产儿支气管肺发育不良(bronchopulmonary dysplasia,BPD)采用布地奈德联合肺表面活性物质(pulmonary surfactant,PS)治疗的临床效果。方法非随机选取2019年3月—2023年3月聊城市人民医院收治的80例BPD早产儿为研究对象。按治疗方法分为两组,每组40例。对照组采用PS治疗,研究组采用布地奈德联合PS治疗。比较两组临床疗效、预后相关指标、血气指标。结果研究组总有效率为95.00%(38/40),高于对照组的77.50%(31/40),差异有统计学意义(χ^(2)=5.165,P<0.05)。研究组给氧、机械通气及住院时间短于对照组,血气指标优于对照组,差异有统计学意义(P均<0.05)。结论布地奈德联合PS治疗早产儿BPD,能够提高临床疗效,改善预后相关指标及血气指标。
Objective To explore the clinical efficacy of budesonide and PS in the treatment of BPD in premature infants.Methods Eighty cases of BPD preterm infants admitted to Liaocheng City People's Hospital from March 2019 to March 2023 were non-randomly selected as study subjects.They were divided into two groups according to the treatment method,with forty cases in each group.The control group was treated with PS,and the study group was treated with budesonide combined with PS.Compared the clinical efficacy,prognosis-related indexes and blood gas indexes of the two groups.Results The total effective rate of the study group was 95.00%(38/40),which was higher than 77.50%(31/40)of the control group,and the difference was statistically significant(χ^(2)=5.165,P<0.05).Oxygen administration,mechanical ventilation and hospitalization time of the study group were shorter than that of the control group,and blood gas indexes of the study group were better than those of the control group,and the differences were statistically significant(all P<0.05).Conclusion Budesonide combined with PS in the treatment of BPD in preterm infants improves clinical efficacy,prognosis-related indicators and blood gas indicators.
作者
徐玉敏
姜中惠
王芳
XU Yumin;JIANG Zhonghui;WANG Fang(Department of Pediatrics,Liaocheng people's Hospital,Liaocheng 252000,Shandong,China)
出处
《系统医学》
2024年第18期143-146,共4页
Systems Medicine
