摘要
目的探讨基于Peplau人际关系理论的系统化干预在淋巴瘤嵌合抗原受体T细胞治疗(CAR-T)患者中的应用效果。方法依据干预方法的不同将135例淋巴瘤CAR-T治疗患者分为对照组(n=68)和观察组(n=67),对照组患者接受常规干预,观察组患者接受基于Peplau人际关系理论的系统化干预。比较两组患者对疾病的恐惧程度[癌症患者恐惧疾病进展简化量表(FoP-Q-SF)]、生活质量[世界卫生组织生存质量测定量表简表(WHOQOL-BREF)]和满意度[纽卡斯尔护理满意度量表(NSNS)]。结果干预后,两组患者生理健康、社会家庭评分均低于本组干预前,观察组患者生理健康、社会家庭评分均低于对照组,差异均有统计学意(P﹤0.05)。干预后,两组患者WHOQOL-BREF各维度评分均高于本组干预前,观察组患者WHOQOL-BREF各维度评分均高于对照组,差异均有统计学意义(P﹤0.05)。观察组患者的总满意度为97.01%,高于对照组患者的85.29%,差异有统计学意义(P﹤0.05)。结论基于Peplau人际关系理论的系统化干预可有效减轻淋巴瘤CAR-T治疗患者对疾病的恐惧程度,提高生活质量,改善满意度。
Objective To investigate the application effect of systematic intervention based on Peplau’s interpersonal relationship theory in lymphoma patients undergoing chimeric antigen receptor T cell therapy(CAR-T).Method A total of 135 lymphoma CAR-T therapy patients were divided into control group(n=68)and observation group(n=67)based on different intervention methods.The control group received routine intervention,while the observation group received systematic intervention based on Peplau’s interpersonal relationship theory.The fear level of disease[fear of progression questionnaire-short form(FoP-Q-SF)],quality of life[World Health Organization quality of life-brief(WHOQOLBREF)]and satisfaction[Newcastle satisfaction with nursing scale(NSNS)]were compared between the two groups.Result After intervention,the physiological health and social family scores of both groups were lower than those before intervention,the physiological health and social family scores of the observation group were lower than those of the control group,and the differences were statistically significant(P<0.05).After intervention,the dimensional scores of WHOQOLBREF in both groups were higher than those before intervention,the dimensional scores of WHOQOL-BREF in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The satisfaction in the observation group was 97.01%,which was higher than 85.29%in the control group,and the difference was statistically significant(P<0.05).Conclusion Systematic intervention based on Peplau’s interpersonal relationship theory can effectively alleviate the fear of lymphoma CAR-T therapy patients towards the disease,improve quality of life,and enhance satisfaction.
作者
郭辰
董蕾
王鹦君
胡丰阳
GUO Chen;DONG Lei;WANG Yingjun;HU Fengyang(Department of Oncology,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,He’nan,China)
出处
《癌症进展》
2024年第18期2002-2005,2014,共5页
Oncology Progress
