摘要
目的:探讨基于“脾主运化”理论的脾运散塌渍腹部在异位妊娠保守治疗中的效果。方法:抽取2022年1月~2023年9月于宜宾市两所中医医院保守治疗的异位妊娠患者60例,按入组顺序随机分为对照组和研究组,对照组采用甲氨蝶呤肌注+米非司酮口服+加味宫外孕II号方口服治疗,研究组在对照组基础上给予脾运散塌渍腹部,观察治疗1周后异位妊娠包块、盆腔积液深度、血绒毛膜促性腺激素(β-HCG)、炎症因子[白介素33(IL-33)、可溶性生长刺激表达基因2蛋白(sST2)]、临床症状消除时间和疗效,并比较治疗完成1个月后输卵管通畅率。结果:两组患者治疗第1、4天包块直径、盆腔积液深度、β-HCG、IL-33和sST2差异无统计学意义(P>0.05),治疗第7天研究组优于对照组(P<0.05)。研究组患者下腹隐痛、腹部压痛和阴道出血消除时间低于对照组(P<0.05)。研究组输卵管总通畅率高于对照组(90.0%vs 63.3%,P<0.05)。研究组保守治疗成功率优于对照组(93.3%vs 73.3%,P<0.05)。结论:脾运散塌渍腹部能加速包块和盆腔积液的消除,降低β-HCG和炎症因子,提高输卵管畅通率。
Objective:To explore the effects of Piyun powder collapsed abdomen in the conservative treatment of ectopic pregnancy masses based on theory of“spleen governing transformation and transportation”.Methods:Sixty patients with ectopic pregnancy who received conservative treatment at two TCM hospitals in Yibin from January 2022 to September 2023 were randomly divided into control group and research group in the order of enrollment.Patients in control group was treated with intramuscular injection of methotrexate,oral administration of mifepristone,and oral administration of modified ectopic pregnancy formula II.Patients in study group was treated with Piyun powder collapsed abdomen on the basis of the control group,and the diameter of ectopic pregnancy masses,the depth of pelvic effusion,blood chorionic gonadotropin(β-HCG),inflammatory factors[interleukin-33(IL-33),soluble growth stimulating gene 2 protein(sST2)],clinical symptom relief time and efficacy was observed after one week of treatment.and compared fallopian tube patency rate after one month of treatment completion.Results:On the first and fourth day of treatment,there was no difference of the diameter of the ectopic pregnancy masses,the depth of pelvic effusion,β-HCG,IL-33,and sST2 levels in both groups(P>0.05),and on the 7th day of treatment,these indexes in research group was better than those in control group(P<0.05).The elimination time of lower abdominal pain,abdominal tenderness,and vaginal bleeding in research group was lower than those in control group(P<0.05).The total patency rate of the fallopian tubes in research group was higher than that in control group(90.0%vs 63.3%,P<0.05).The success rate of conservative treatment in research group was better than that in control group(93.3%vs 73.3%,P<0.05).Conclusion:Piyun powder collapsed abdomen can accelerate the elimination of masses and pelvic effusion,and reduceβ-HCG and inflammatory factors and improve the patency of the fallopian tubes.
作者
胡雪梅
胡道敏
程勤
王江燕
马建榕
夏雪怡
HU Xuemei;HU Daomin;CHENG Qin(Department of Gynaecology and Obstetrics,The Second TCM Hospital of Yibin,Yibin Sichuan 644000,China;Department of Nursing,The Second TCM Hospital of Yibin,Yibin Sichuan 644000,China)
出处
《四川中医》
2024年第10期158-162,共5页
Journal of Sichuan of Traditional Chinese Medicine
基金
宜宾市科学技术局中医药领域科技计划项目(编号:2021ZYY021)。
关键词
脾运散
脾主运化
异位妊娠
保守治疗
Piyun powder
Spleen governing transformation and transportation
Ectopic pregnancy
Conservative treatment
