摘要
目的评估超声灰阶直方图测量计算的胰脾超声灰阶比(UGSR)诊断非酒精性脂肪性胰腺疾病(NAFPD)的临床价值,分析其相关影响因素。方法选取于我院行腹部平扫CT及超声检查的95例住院患者,根据CT结果分为NAFPD组(44例)和非NAFPD组(51例)。应用超声灰阶直方图测量患者胰腺、脾脏感兴趣区(ROI)平均灰阶值,计算二者比值即为胰脾UGSR;比较两组胰脾UGSR和临床资料的差异。采用单因素及多因素线性回归分析筛选胰脾UGSR的影响因素;绘制受试者工作特征(ROC)曲线分析胰脾UGSR对NAFPD的诊断效能。结果NAFPD组与非NAFPD组年龄、体质量指数(BMI)、收缩压、舒张压、空腹血糖(FBG)、总胆固醇(TG)、甘油三酯(TC)、高密度脂蛋白、低密度脂蛋白(LDL)、丙氨酸氨基转移酶和胰脾UGSR比较差异均有统计学意义(均P<0.05),性别、门冬氨酸氨基转移酶比较差异均无统计学意义。单因素线性回归分析显示,年龄、BMI、血压、FBG、TG、TC、LDL均为胰脾UGSR的影响因素(均P<0.05):多因素线性回归分析显示,BMI、FBG均为胰脾UGSR的独立影响因素(均P<0.05)。ROC曲线分析显示,胰脾UGSR诊断NAFPD的曲线下面积为0.929(95%可信区间:0.858~0.972),以1.64为截断值,对应的灵敏度为97.73%,特异度为88.24%。结论超声灰阶直方图测量计算的胰脾UGSR在NAFPD诊断中具有一定的临床价值,且BMI、FBG均为胰脾UGSR的独立影响因素。
Objective To analyze the relevant influencing factors of pancreatic-splenic ultrasound grayscale ratio(UGSR)measured and calculated by ultrasound gray-scale histogram,and to assess the clinical value the diagnosis of nonalcoholic fatty pancreas disease(NAFPD).Methods Ninety-five inpatients patients who underwent abdominal CT and ultrasound at our hospital were selected.According to the CT diagnostic results,all patients were divided into the NAFPD group(44 cases)and the non-NAFPD group(51 cases).The average gray-scale value of the region of interest(ROI)of the pancreas and spleen were measured by gray-scale histograms,and the ratio of these values was calculated as the pancreatic-splenic UGSR.The differences of pancreatic-splenic UGSR and clinical data between the two groups were compared.Univariate and multivariate linear regression analysis were used to screen the influencing factors of pancreatic-splenic UGSR.Receiver operating characteristic(ROC)curve was drawn to evaluate the diagnostic performance of pancreatic-splenic UGSR for NAFPD.Results There were statistically significant differences in age,body mass index(BMI),systolic blood pressure,diastolic blood pressure,fasting blood glucose(FBG),triglycerides(TG),total cholesterol(TC),high-density lipoprotein,low-density lipoprotein(LDL),alanine aminotransferase and pancreatic-splenic UGSR between the NAFPD group and the non-NAFPD group(all P<0.05),while there were no statistically significant differences in gender and aspartate aminotransferase.Univariate linear regression analysis indicated that age,BMI,blood pressure,FBG,TG,TC and LDL were influencing factors of pancreatic-splenic UGSR(all P<0.05).Multivariate linear regression analysis showed that BMI and FBG were independent influencing factors of pancreatic-splenic UGSR(both P<0.05).ROC curve analysis showed that the area under the curve of pancreatic-splenic UGSR for diagnosing NAFPD was 0.929(95%confidence interval:0.858~0.972),with a cutoff value of 1.64,corresponding to a sensitivity of 97.73%and a sp
作者
毕士玉
卢天祺
周康
杨秀华
BI Shiyu;LU Tianqi;ZHOU Kang;YANG Xiuhua(Department of Qunli Ultrasound Medicine,the First Affiliated Hospital of Harbin Medical University,Harbin 150000,China)
出处
《临床超声医学杂志》
CSCD
2024年第10期823-827,共5页
Journal of Clinical Ultrasound in Medicine
关键词
超声检查
灰阶直方图
超声灰阶比
非酒精性脂肪胰腺疾病
Ultrasonography
Gray-scale histogram
Ultrasound grayscale ratio
Non-alcoholic fatty pancreatic disease
