期刊文献+

胶质瘤化疗中国专家共识

Chinese experts consensus on chemotherapy for glioma
下载PDF
导出
摘要 胶质瘤是最常见的颅内原发性恶性肿瘤。目前,治疗以手术切除为主,辅以放疗和化疗。临床实践证明,胶质瘤化疗极具意义,已被广泛应用于新诊断的胶质瘤术后辅助治疗和复发胶质瘤的挽救治疗。为进一步规范胶质瘤的化疗过程,提高治疗效果,中国抗癌协会神经肿瘤专业委员会组织相关专家,编写了《胶质瘤化疗中国专家共识》(以下简称《共识》),为广大同仁提供临床实际操作参考。《共识》从胶质瘤化疗相关的病理知识、化疗过程中患者管理、影像学评价、不同级别胶质瘤、新诊断或复发患者、如何结合其他治疗策略等角度对化疗方案进行了介绍。 Glioma is the most prevalent primary intracranial malignant tumor.At present,the main therapy is surgical resection,supplemented by radiotherapy and chemotherapy.Clinical practice has demonstrated that chemotherapy is highly significant and widely employed in postoperative adjuvant therapy for newly diagnosed gliomas as well as salvage therapy for recurrent cases.In order to further standardize the chemotherapy process of glioma and improve the therapeutic effect,Chinese experts consensus on chemotherapy for glioma was compiled by relevant experts organized by Chinese Society of Neuro-oncology,which aims to provide clinical reference for colleagues during neuro-oncology practice.The consensus introduces the chemotherapy regimen from the perspectives of pathological knowledge related to glioma chemotherapy,patient management during chemotherapy,imaging evaluation,different grades of glioma,newly diagnosed or relapsed patients and how to combine other treatment strategies.
出处 《中国神经精神疾病杂志》 CAS CSCD 北大核心 2024年第8期449-462,共14页 Chinese Journal of Nervous and Mental Diseases
关键词 胶质瘤 高级别胶质瘤 化疗策略 化疗方案 专家共识 Glioma High grade glioma Chemotherapy strategies Chemotherapy regimens Consensus of Chi-nese experts
  • 相关文献

参考文献8

二级参考文献54

  • 1陈忠平.重视胶质瘤的化学治疗[J].中国神经肿瘤杂志,2003,1(2):65-68. 被引量:11
  • 2张俊英,陈忠平.MGMT基因表达与人脑胶质瘤化疗耐药关系研究[J].中国神经肿瘤杂志,2003,1(4):200-204. 被引量:12
  • 3曾宪起,申长虹,浦佩玉,杨树源.应用替莫唑胺对照司莫司丁治疗恶性脑胶质瘤的疗效观察[J].中华神经外科杂志,2006,22(4):204-207. 被引量:50
  • 4Hegi ME, Diserens AC, Godard S, et al. Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide. Clin Cancer Res, 2004, 10: 1871-1874. 被引量:1
  • 5Hegi ME, Diserens AC, Gorlia T, et al. MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med, 2005, 352: 997-1003. 被引量:1
  • 6Preuss I, Thust R, Kaina B. Protective effect of O^6-methylguanine-DNA methyltransferase (MGMT) on the cytotoxic and recombinogenic activity of different antineoplastic drugs. Int J Cancer, 1996,65 : 506-512. 被引量:1
  • 7D'Atri S, Graziani G, Lacal PM, et al. Attenuation of O (6)- methylguanine-DNA methyltransferase activity and mRNA levels by cisplatin and temozolomide in jurkat ceils. J Pharmacol Exp Ther, 2000,294:664-671. 被引量:1
  • 8Tolcher AW, Gerson SL, Denis L, et al. Marked inactivation of O^6-alkylguanine-DNA alkyltransferase activity with protracted temozolomide schedules. Br J Cancer, 2003,88 : 1004-1011. 被引量:1
  • 9Patrick Y. Wen MD,Santosh Kesari MD, PhD. Malignant gliomas[J] 2004,Current Neurology and Neuroscience Reports(3):218~227 被引量:1
  • 10M. Bower,E. S. Newlands,N. M. Bleehen,M. Brada,R. J. H. Begent,H. Calvert,I. Colquhoun,P. Lewis,M. H. Brampton. Multicentre CRC phase II trial of temozolomide in recurrent or progressive high-grade glioma[J] 1997,Cancer Chemotherapy and Pharmacology(6):484~488 被引量:1

共引文献435

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部