摘要
目的分析腹腔镜手术治疗胃十二指肠溃疡穿孔的效果及对其术后并发症的影响。方法选取2020年4月-2023年4月我院接诊的54例胃十二指肠溃疡穿孔患者为研究对象,采用随机数字表法分为对照组(n=27)和观察组(n=27)。对照组采用常规开腹手术治疗,观察组采用腹腔镜手术治疗,比较两组临床手术指标、疼痛评分(VAS)、胃肠功能指标[胃动素(MTL)、胃泌素(GAS)]、应激反应指标[C反应蛋白(CRP)、白细胞介素(IL-6)]、并发症发生率。结果观察组手术时间、下床活动时间、首次排气时间、住院时间均短于对照组,术中出血量少于对照组(P<0.05);观察组术后6、12 h的VAS评分均低于对照组(P<0.05);两组术后MTL、GAS均高于术前,且观察组高于对照组(P<0.05);观察组术后第3天CRP、IL-6水平均低于对照组(P<0.05);观察组并发症发生率为3.70%,低于对照组的14.81%(P<0.05)。结论腹腔镜手术治疗胃十二指肠溃疡穿孔的效果确切,可改善手术指标,减轻应激反应,降低疼痛程度及并发症发生率,利于术后胃肠功能恢复,值得临床加以应用。
Objective To analyze the effect of laparoscopic surgery in the treatment of gastroduodenal ulcer perforation and its influence on postoperative complications.Methods A total of 54 patients with gastroduodenal ulcer perforation admitted to our hospital from April 2020 to April 2023 were selected as the research objects.They were divided into control group(n=27)and observation group(n=27)by random number table method.The control group was treated with conventional laparotomy,and the observation group was treated with laparoscopic surgery.The clinical operation indexes,pain score(VAS),gastrointestinal function indexes[motilin(MTL),gastrin(GAS)],stress response indexes[C-reactive protein(CRP),interleukin(IL-6)]and complication rate were compared between the two groups.Results The operation time,ambulation time,first exhaust time and hospitalization time of the observation group were shorter than those of the control group,and the intraoperative blood loss was less than that of the control group(P<0.05).The VAS score of the observation group at 6 and 12 h after operation was lower than that of the control group(P<0.05).The MTL and GAS of the two groups after operation were higher than those before operation,and those of the observation group were higher than those of the control group(P<0.05).The levels of CRP and IL-6 in the observation group were lower than those in the control group on the 3rd day after operation(P<0.05).The incidence of complications in the observation group was 3.70%,which was lower than 14.81%in the control group(P<0.05).Conclusion Laparoscopic surgery is effective in the treatment of gastroduodenal ulcer perforation,which can improve the surgical indicators,reduce the stress response,reduce the degree of pain and the incidence of complications.Meanwhile,it is conducive to the recovery of gastrointestinal function after surgery,and is worthy of clinical application.
作者
姚滨
YAO Bin(The First Department of Surgery,Anfu County Hospital of Traditional Chinese Medicine,Anfu 343200,Jiangxi,China)
出处
《医学信息》
2024年第20期120-122,126,共4页
Journal of Medical Information
关键词
腹腔镜手术
胃十二指肠溃疡穿孔
胃肠功能
Laparoscopic surgery
Perforation of gastroduodenal ulcer
Gastrointestinal function
