摘要
Hydrogels have been the subject of significant research in the field of friction due to their exceptional lubricating properties.In this study,the G-quadruplex hydrogel with high selectivity for K^(+) ions was formed by introducing a mixture of G,2-formylphenylboronic acid,and polyethylene glycol diamine into simulated artificial tears solution with high transparency,and an ultra-low coefficient of friction(COF)of about 0.004 was obtained based on the simulated ocular environment,thus achieving macroscopic superlubricity.In friction pairs simulating the ocular environment,to assess the frictional performance of the G-quadruplex hydrogel as both a lubricant and a friction pair based on the simulated ocular environment,we conducted experiments considering various factors such as concentration,sliding speed,and stress.Through these experiments,it was found that superlubricity was achieved when the G-quadruplex hydrogel was applied as lubricant or friction pair.This effect was attributed to the three-dimensional network structure and hydrophilicity of the hydrogel,which facilitated the formation of a highly bearing and flowing hydration layer,promoting macroscopic superlubricity.Compared to the G-quadruplex hydrogel with low concentration,the high concentration hydrogel(75 mM)exhibited increased mechanical strength and robustness in superlubricity.Combined with biocompatibility experiments,our synthesized G-quadruplex hydrogel has excellent biocompatibility and offers a novel approach to achieve superlubricity in ocular drug delivery.
出处
《Friction》
SCIE
EI
CAS
CSCD
2024年第11期2548-2562,共15页
摩擦（英文版）
基金
supported by the National Natural Science Foundation of China(Grant Nos.52275203 and 52105194)
China Postdoctoral Science Special Funding Project(Grant No.2022T150353)
the Tribology Science Fund of State Key Laboratory of Tribology in Advanced Equipment(Grant Nos.SKLTKF20A01 and SKLTKF23A04).
