摘要
目的观察热敏灸联合克罗米芬治疗多囊卵巢综合征不孕的临床疗效。方法将符合纳入标准的64例肾阳虚型多囊卵巢综合征不孕患者按随机数字表法分为观察组和对照组,每组32例。对照组采用克罗米芬治疗,观察组采用热敏灸联合克罗米芬治疗。比较两组治疗前后子宫内膜和卵泡直径的变化,比较两组排卵情况、妊娠情况和临床疗效。结果两组治疗后最大卵泡直径和子宫内膜厚度均较治疗前增加(P<0.05),且观察组均优于对照组(P<0.05)。观察组排卵次数为47次,未排卵次数为6次,排卵率为88.7%;对照组排卵次数为31次,未排卵次数为9次,排卵率为77.5%;两组排卵率比较差异无统计学意义(P>0.05)。观察组妊娠12例,未妊娠20例;对照组妊娠7例,未妊娠25例;组间差异无统计学意义(P>0.05)。观察组总有效率为87.5%,高于对照组的62.5%,差异有统计学意义(P<0.05)。结论热敏灸联合克罗米芬治疗多囊卵巢综合征不孕可增加子宫内膜厚度,增大卵泡直径,促进排卵,临床疗效优于单纯克罗米芬治疗。
Objective To observe the clinical efficacy of treating infertility in polycystic ovary syndrome(PCOS)with heat-sensitive moxibustion plus Clomiphene citrate.Method Sixty-four eligible patients with PCOS-induced infertility of kidney Yang deficiency pattern were divided into an observation group and a control group using the random number table method,with 32 cases in each group.The control group was treated with Clomiphene citrate,and the observation group was offered heat-sensitive moxibustion plus Clomiphene citrate.Before and after the treatment,changes in the endometrium and follicle diameter were compared before and after the treatment.The two groups were also compared in terms of ovulation,pregnancy outcomes,and clinical efficacy.Result After the treatment,the maximum follicle diameter and the endometrium thickness increased in both groups(P<0.05),and those in the observation group were superior to those in the control group(P<0.05).The observation group had 47 ovulation times and 6 anovulation times,obtaining an ovulation rate of 88.7%,and the control group had 31 ovulation times and 9 anovulation times,obtaining an ovulation rate of 77.5%;there was no significant difference in the ovulation rate between the two groups(P>0.05).There were 12 pregnant cases and 20 nonpregnant cases in the observation group versus 7 and 25 cases in the control group;the difference was statistically insignificant between the two groups(P>0.05).The total effective rate was 87.5%in the observation group,higher than 62.5%in the control group,and the difference was statistically significant(P<0.05).Conclusion In the treatment of PCOS-induced infertility,heat-sensitive moxibustion plus Clomiphene citrate can increase endometrium,enlarge follicle diameter,and promote ovulation,producing more significant efficacy than using Clomiphene citrate alone.
作者
杨易
叶文国
陈晓勇
章根平
YANG Yi;YE Wenguo;CHEN Xiaoyong;ZHANG Genping(Jiangxi Maternal and Child Health Hospital,Nanchang 330006,China;Jiangxi Key Laboratory of Female Reproduction of Integrated Traditional Chinese and Western Medicine,Nanchang 330006,China;Jiangxi Gynecological Disease Diagnosis and Treatment Center of Integrated Traditional Chinese and Western Medicine,Nanchang 330006,China;The Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine,Nanchang 330006,China;Jiangxi Nanchang Fourth Hospital,Nanchang 330006,China)
出处
《上海针灸杂志》
CSCD
2024年第10期1051-1055,共5页
Shanghai Journal of Acupuncture and Moxibustion
基金
江西省中医药管理局科技计划项目(2020B0057)
江西省教育厅科学技术研究项目青年项目(190687)。
关键词
灸法
热敏灸
多囊卵巢综合征
不育
女性
不孕症
肾阳虚
Moxibustion
Heat-sensitive moxibustion
Polycystic ovary syndrome
Infertility,Female
Sterility
Kidney Yang deficiency
