摘要
壮肝逐瘀煎是目前广西治疗肝脏相关疾病的常用效方,近年来广泛应用于肝纤维化、肝硬化、肝癌等治疗中。该文通过对信号通路研究的检测指标及结果进行分析归纳,发现在信号通路方面有多元化,多角度的研究趋势,目前研究以转化生长因子-β1/Smads为主;25篇文献研究中,有24篇明确提及壮肝逐瘀煎具有明显的抗肝纤维化甚至是逆转肝纤维化的作用,为进一步拓宽临床使用范围提供了重要的理论基础和科学依据。
Zhuanggan Zhuyu Decoction(壮肝逐瘀煎)is a commonly used prescription for the treatment of liver-related diseases in Guangxi,and has been widely used in the treatment of liver fibrosis,cirrhosis and liver cancer in recent years.Through the analysis and summary of the detection indicators and results of the signaling pathway research,it is found that there is a diversified and multi-angle research trend in the signaling pathway,and the current research mainly focuses on transforming growth factor-β1/Smads.Among the 25 literature studies,24 articles explicitly mentioned that Zhuanggan Zhuyu Decoction had obvious anti-liver fibrosis or even reverse liver fibrosis,which provided an important theoretical basis and scientific basis for further expanding clinical use.
作者
李爽
梁尧
刘旭东
曹丽
苏生勤
翁晓新
胡玥晗
刘振威
LI Shuang;LIANG Yao;LIU Xudong;CAO Li;SU Shengqin;WENG Xiaoxin;HU Yuehan;LIU Zhenwei(Guangxi University of Chinese Medicine,Nanning 530200,Guangxi,China;The First Affiliated Hospital of Guangxi University of Chinese Medicine,Nanning 530022,Guangxi,China;Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine,Nanning 530011,Guangxi,China)
出处
《实用中医内科杂志》
2024年第10期52-56,共5页
Journal of Practical Traditional Chinese Internal Medicine
基金
第七批全国老中医药专家学术经验继承项目(2021007)
广西中医药大学桂派中医药传承创新团队资助项目(2022B004)。
关键词
壮肝逐瘀煎
信号通路
肝炎
肝纤维化
肝硬化
Zhuanggan Zhuyu Decoction(壮肝逐瘀煎)
signal path
hepatitis
liver fibrosis
liver cirrhosis
