摘要
目的:探讨影响首次青年缺血性脑卒中(IS)患者住院7 d及出院90 d预后的危险因素。方法:回顾性收集2022年2月—2023年9月蚌埠市第三人民医院住院治疗的81例IS患者一般资料,根据住院7 d时改良RANKIN量表(mRS)评分分为住院7 d预后不良组(mRS≥2分)(18例)及住院7 d预后良好组(mRS<2分)(63例);根据出院90 d时mRS评分分为出院90 d预后不良组(mRS≥2分)(12例)及出院90 d预后良好组(mRS<2分)(69例)。采用多因素Logistic回归分析影响患者住院7 d及出院90 d预后不良的独立危险因素。结果:单因素分析结果显示,住院7 d预后不良组入院美国国立卫生研究院卒中量表(NIHSS)评分、2型糖尿病比例,总胆固醇(TC),甘油三酯(TG),低密度脂蛋白胆固醇(LDL-C)、同型半胱氨酸(Hcy)水平及甘油三酯葡萄糖乘积(TyG)指数均高于住院7 d预后良好组(P<0.05);出院90 d预后不良组入院NIHSS评分、2型糖尿病比例、TG、Hcy水平、TyG指数均高于预后良好组(P<0.05)。Logistic回归分析结果示,入院NIHSS评分(OR=2.056,95%CI:1.010~4.187)、TyG指数(OR=2.139,95%CI:1.039~4.402)为住院7 d预后不良的独立危险因素(P<0.05);入院NIHSS评分(OR=2.949,95%CI:1.141~7.620)、TyG指数(OR=5.026,95%CI:1.047~5.088)和血清Hcy(OR=2.075,95%CI:1.023~4.210)为出院90 d预后不良的独立危险因素(P<0.05)。结论:TyG指数、入院NIHSS评分高为影响首次青年IS患者住院7d预后的独立危险因素,而TyG指数、入院NIHSS评分及血清Hcy水平高是出院90 d预后的独立危险因素。
Objective:To explore the factors that influence prognosis of first-time young ischemic stroke(IS)patients 7 days after hospitalization and 90 days after discharge.Methods:General data of 81 patients with IS who were hospitalized in Bengbu Third People's Hospital from February 2022 to September 2023 were collected.According to the modified RANKIN scale(mRS)score at 7 days after hospitalization,the patients were divided into a poor prognosis group(mRS≥2 points)(18 cases)and a good prognosis group(mRS<2 points)(63 cases).Based on the mRS score at 90 days after discharge,the patients were divided into a poor prognosis group(mRS≥2 points)(12 cases)and a good prognosis group(mRS<2 points)(69 cases).Univariate analysis was used to compare the risk factors between the poor prognosis group and the good prognosis group,and multi-factor Logistic regression was used to analyze the independent risk factors affecting the poor prognosis at 7 days in hospital and 90 days after discharge.Results:The results of single factor analysis showed that in the 7d hospitalization group,National Institutes of Health Stroke Scale(NIHSS),rate of type 2 diabetes,total cholesterol,triglyceride,lowdensity lipoprotein(LDL),homocysteine(Hcy)and TyG indexes were higher than those in the good prognosis group(P<0.05).At 90 days after discharge,NIHSS,rate of type 2 diabetes,total cholesterol,Hcy,and TyG indexes in the poor prognosis group were higher than those in the good prognosis group(all P<0.05).Logistic regression analysis showed that NIHSS(OR=2.056,95%CI:1.010~4.187)and TyG index(OR=2.139,95%CI:1.039~4.402)were independent risk factors for poor prognosis on the 7th day after hospitalization(P<0.05).NIHSS(OR=2.949,95%CI:1.141~7.620),TyG index(OR=5.026,95%CI:1.047~5.088)and Hcy(OR=2.075,95%CI:1.023~4.210)were independent risk factors for poor prognosis at 90 days after discharge(P<0.05).Conclusion:High TyG index and high NIHSS on admission were the independent risk factors for the prognosis of young first-time IS patients at 7 days after hosp
作者
刘莎
李士尊
LIU Sha;LI Shizun(Department of Neurology,The Third People's Hospital of Bengbu,Bengbu,Anhui 233000,China)
出处
《淮海医药》
CAS
2024年第5期458-461,共4页
Journal of Huaihai Medicine
关键词
缺血性脑卒中
青年
预后
影响因素
Ischemic stroke
Youth
Prognosis
Influencing factors
