摘要
目的系统评价我国在院急性心肌梗死(AMI)患者便秘的发生率,为AMI患者在院期间便秘的管理提供参考。方法系统检索中国知网、万方、维普、中国生物医学文献数据库、PubMed、Cochrane数据库、Embase和Web of Science,检索时限为建库至2024年2月4日,选取有关我国在院AMI患者便秘发生情况的相关研究,并进行规范的文献质量评价,采用STATA17.0软件进行率的meta分析。结果共纳入文献34篇,包括3504例在院AMI患者,便秘者1134例。经meta整合分析,我国在院AMI患者便秘的发生率为37.4%[95%可信区间(95%CI)0.300~0.450]。亚组分析显示,2006-2011年的在院AMI患者便秘发生率最高,为50.6%(95%CI 0.414~0.598),2017-2021年的便秘发生率最低,为28.8%(95%CI 0.169~0.408);中医院的在院AMI患者便秘发生率(39.2%,95%CI 0.271~0.514)高于综合医院(36.7%,95%CI 0.279~0.456);北方在院AMI患者(42.0%,95%CI 0.313~0.527)高于南方的便秘发生率(35.5%,95%CI 0.266~0.443);根据便秘诊治指南检测出的便秘发生率(39.2%,95%CI 0.323~0.461)高于临床定义的便秘检出率(35.9%,95%CI 0.256~0.461)。结论我国在院AMI患者便秘的发生率较高,临床医务工作者可结合临床采取针对性措施对AMI患者便秘进行预防和管理。
Objective To systematically evaluate the incidence of constipation in hospitalized patients with acute myocardial infarction(AMI)in China,and to provide reference for the management of constipation in hospitalized patients with AMI.Methods The CNKI,Wanfang,VIP,China Biomedical Literature Database,PubMed,Cochrane Database,Embase and Web of Science were systematically searched,and the retrieval time was from to February 4,2024.Relevant studies on constipation in hospitalized patients with AMI in China were selected,and the standard literature quality was evaluated,and the meta-analysis of the rate was carried out by STATA17.0 software.Results A total of 34 studies were included,including 3504 hospitalized patients with AMI and 1134 patients with constipation.According to meta integration,the incidence of constipation in hospitalized patients with AMI in China was 37.4%[95%confidence(95%CI)0.300-0.450].Subgroup analysis showed that the highest rate of constipation was 50.6%(95%CI 0.414-0.598)in 2006-2011,and the lowest rate was 28.8%(95%CI 0.169-0.408)in 2017-2021;the incidence of constipation in traditional Chinese medicine hospitals(39.2%,95%CI 0.271-0.514)was higher than that in general hospitals(36.7%,95%CI 0.279-0.456);the incidence of constipation in the hospitalized patients with AMI in the north(42.0%,95%CI 0.313-0.527)was higher than that in the south(35.5%,95%CI 0.266-0.443);The incidence of constipation detected according to the guidelines for diagnosis and treatment of constipation(39.2%,95%CI 0.323-0.461)was higher than that defined by clinical definition(35.9%,95%CI 0.256-0.461).Conclusion The incidence of constipation in hospitalized patients with AMI is high in China.Clinical medical workers can take targeted measures to prevent and manage constipation in patients with AMI in combination with clinical practice.
作者
孙春艳
胡蕾
徐南娇
SUN Chunyan;HU Lei;XU Nanjiao(Nanjing University Medical School Affiliated Hospital of Gulou,Nanjing,Jiangsu 210008,China)
出处
《现代医药卫生》
2024年第19期3330-3336,共7页
Journal of Modern Medicine & Health
基金
南京鼓楼医院临床研究专项资金项目(2022-LCYJ-PY-23)
南京大学医学院附属鼓楼医院院级课题(2023-A1470、2024-A1470)
南京大学中国医院改革发展研究院课题项目
南京鼓楼医院医学发展医疗救助基金会资助项目(NDYGN2023064)。
关键词
在院患者
急性心肌梗死
便秘
META分析
Hospitalized patients
Acute myocardial infarction
Constipation
Meta-analysis
