摘要
目的统计2017年1月至2022年12月滨州医学院附属医院皮肤性病科门诊就诊患者梅毒感染情况,分析其感染率及流行趋势,为制定梅毒防控措施提供依据。方法收集自愿进行梅毒检测患者的一般资料、梅毒螺旋体颗粒凝集试验(TPPA)和快速血浆反应素试验(RPR)检测数据,并进行统计学处理和分析。结果2017至2022年,该院皮肤性病科门诊累计筛查患者6290例,阳性感染者3198例,年筛查人群阳性感染率分别为54.58%、53.19%、52.35%、49.79%、46.21%、45.89%。现症感染者1321例(21.00%),年筛查人群现症感染率分别为23.21%、21.84%、20.99%、19.72%、19.53%、19.45%。感染高发年龄主要集中在21~40岁。感染人群中女性占比高于男性(P<0.05),性别比例为1:0.89。2017至2019年女性占比分别为51.92%、53.19%、58.24%,呈逐年上升趋势,而2020至2022年女性占比明显下降,分别为50.32%、50.81%、50.27%。结论梅毒感染率整体呈缓慢降低趋势,21~40岁为梅毒感染高发年龄段,女性感染率高于男性,而40岁以后女性则低于男性。因此,应加大对梅毒等性传播疾病的监测力度。
Objective To investigate the incidence of patients with syphilis at dermatology clinic in Binzhou Medical University Hospital bewteen January 2017 and December 2022,and analyze its infection rate and epidemic trend,so as to provide an important basis for the control strategy of syphilis.Methods The general data of patients who voluntarily underwent syphilis testing,along with their corresponding test results in treponema pallidum particle agglutination(TPPA)and rapid plasma reagin(RPR)were collected for statistical analysis.Results A total of 6290 cases were tested from 2017 to 2022,with 3198 cases yielding positive results.The annual positive rates were 54.58%,53.19%,52.35%,49.79%,46.21%and 45.89%,respectively.There were 1321(21.00%)cases with current infection,and the annual current infection rates were 23.21%,21.84%,20.99%,19.72%,19.53%and 19.45%,respectively.The majority of cases fell within the age range of 21-40 years.The proportion of infection was significantly higher in females compared to males(P<0.05),with a female to male ratio of 1:0.89.The proportions of infection in females were 51.92%、53.19%and 58.24%respectively from 2017 to 2019,showing a consistent year-on-year growth trend.However,there was a significant decline in the proportions of infection in females at 50.32%,50.81%,and 50.27%from 2020 to 2022.Conclusion The incidence of syphilis is decreasing slowly year by year.The majority of cases occurred among individuals aged 21-40 years.While the incidence rate was higher in females compared to males,the incidence rate among females over 40 years old was lower than that among males.Therefore,enhanced monitoring measures should be implemented for sexually transmitted diseases such as syphilis.
作者
刘静
安荣真
郭科
LIU Jing;AN Rongzhen;GUO Ke(Department of Blood Transfusion,Binzhou Medical University Hospital,Binzhou 256600,China)
出处
《实用皮肤病学杂志》
2024年第4期211-213,F0003,共4页
Journal of Practical Dermatology
关键词
梅毒
感染率
流行趋势
防控措施
Syphilis
Incidence rate
Epidemic trend
Prevention and control measures
