摘要
“肺朝百脉”是指以肺气宣发肃降为动力,以肺生血为物质基础,调节周身血脉。肾素血管紧张素系对血管的作用同“肺朝百脉”有着密切联系。肾素血管紧张素系统通过ACE-Ang II-AT1R轴与ACE2-Ang-(1-7)-MasR轴在肺间质纤维化过程中起重要调节作用。基于“肺朝百脉”理论,阐述肾素血管紧张素系统在肺间质纤维化形成中的意义,为中医药改善间质性肺疾病提供新的思路和研究方法。
"The Convergence of Vessels in the Lung"refers to the pulmonal-qi dispersion and descending as the driving force and the pulmonal-blood production as the material basis to regulate blood vessels throughout the body.The effect of renin-angiotensin system on the blood vessels is closely related to the"the Convergence of Vessels in the Lung".The renin-angiotensin system plays an important regulation role in the process of pulmonary interstitial fibrosis through ACE-Ang II-AT1R axis and ACE2-Ang-(1-7)-MASr axis.Based on the theory of"the Convergence of Vessels in the Lung",the significance of the renin-angiotensin system in the formation of interstitial pulmonary fibrosis is expounded,providing a new idea and research method for improving interstitial pulmonary diseases with traditional Chinese medicine.
作者
满孝君
马君
MAN Xiao-jun;MA Jun(Shandong University of Traditional Chinese Medicine,Jinan 250014,China;The Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250014,China)
出处
《云南中医中药杂志》
2024年第9期16-21,共6页
Yunnan Journal of Traditional Chinese Medicine and Materia Medica
基金
山东省中医药科技发展计划项目(2019-0127)。
关键词
间质性肺疾病
肺间质纤维化
肺朝百脉
宣发肃降
肺生血
肾素血管紧张素系统
血管紧张素Ⅱ
Interstitial Lung Disease
Pulmonary Interstitial Fibrosis
"Convergence of Vessels in the Lung"
Dispersion and Descending
Pulmonal-blood Production
Renin-angiotensin System
Angiotensin II
