摘要
目的分析中医药治疗外感寒、热及外寒内热型咳嗽用药特点,为临床用药提供参考。方法通过查阅中医古籍、中国学术期刊全文数据库(CNKI)、万方数据库(Wanfang Data)、维普生物医学数据库(VIP)等平台检索筛选中药治疗风寒袭肺、风热犯肺和外寒内热型咳嗽的处方,使用中医传承辅助平台(V2.5)分析3类证型处方中药的药物频次、性味归经、关联规则分析。结果风寒袭肺型咳嗽共包含处方263条,184味中药,其中使用频次较高的有甘草、杏仁、麻黄、桔梗、半夏、陈皮等中药。风热犯肺型咳嗽共包含处方314条,217味中药,其中使用频次较高的有甘草、杏仁、桔梗、黄芩、麻黄、桑白皮等药物。外寒内热型咳嗽共包含处方102条,有128味中药,其中使用频次较高的有甘草、杏仁、麻黄、黄芩、半夏、桔梗等药物。结论统计分析结果表明治疗3类证型咳嗽多以解表药、止咳化痰药、理气药为主,药性多温、平,药味辛、甘,归入肺、脾经等。
Objective To analyze the characteristics of traditional Chinese medicine(TCM)medications used in the treatment of externally induced cold,heat and externally cold and internally heated coughs,and to provide a reference for clinical use of medications.Methods Searching and screening the prescriptions of traditional Chinese medicine for the treatment of wind-cold attacking the lungs,wind-heat attacking the lungs,and external-cold and internal-heat type of coughs by consulting ancient Chinese medical writings and books,platforms of China National Knowledge Infrastructure,Wanfang Data,VIP Database for Chinese Technical Periodicals,The frequency of drugs,medicinal flavor attribution,association rule analysis were analyzed using the Traditional Chinese Medicine Inheritance Support System(V2.5).Results Prescription for wind-cold-attacked lung-type cough contained 263 prescriptions and 184 Chinese herbal medicines,of which those used more frequently included Glycyrrhizae Radix et Rhizoma,Armeniacae Semen Amarum,Ephedrae Herba,Platycodon Radix,Pinelliae Rhizoma,Citri Reticulatae Pericarpium.Prescription for wind-heat-affected lung cough contained a total of 314 prescriptions and 217 Chinese herbal medicines,among which Glycyrrhizae Radix et Rhizoma,Armeniacae Semen Amarum,Platycodon Radix,Scutellariae Radix,Ephedrae Herba,and Mori Cortex were used more frequently.Prescription for the external cold and internal heat type of cough contained a total of 102 prescriptions with 128 Chinese herbal medicines,among which the more frequently used medicines were Glycyrrhizae Radix et Rhizoma,Armeniacae Semen Amarum,Ephedrae Herba,Scutellariae Radix,Pinelliae Rhizoma,Platycodon Radix.Conclusion Statistical analysis of the results showed that the treatment of the three types of cough is mostly based on diaphoretic,cough phlegm medicine,qi-regulating medicine,the nature of the medicine is mostly warm,flat,the taste of the medicine is pungent,sweet,and attributed to the lung and spleen meridians,etc.,which provides a certain reference f
作者
赵孟楠
龚苏晓
魏雨清
杨婧萱
王帅
单淇
周福军
ZHAO Mengnan;GONG Suxiao;WEI Yuqing;YANG Jingxuan;WANG Shuai;SHAN Qi;ZHOU Fujun(Graduate School,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China;State Key Laboratory of Druggability Evatuation and Systematic Translational Medicine,Tianjin 300301,China;Tianjin Key Laboratory of Quality Marker of Traditional Medicine,Tianjin 300301,China;Tianjin Institute of Pharmaceutical Research,Tianjin 300301,China;Tipr HUYA Advancing Innovative Medicines Ltd.,Tianjin 300301,China)
出处
《药物评价研究》
CAS
北大核心
2024年第9期2147-2156,共10页
Drug Evaluation Research
基金
安徽省科技重大专项计划(202303a07020007)
广西创新驱动发展专项资金资助项目(桂科A A 18118049-3)。
关键词
咳嗽
风寒袭肺
风热犯肺
外寒内热
数据分析
中医传承辅助平台
cough
wind-cold attack the lung
wind-heat affects the lung
external cold and internal heat
data analysis
Traditional Chinese Medicine Inheritance Support System
