摘要
目的评析在老年患者无痛可弯曲支气管镜诊疗中,采用苯磺酸瑞马唑仑复合阿芬太尼的麻醉效果。方法选择100例接受无痛可弯曲支气管镜诊疗的老年患者,根据随机数字表法分为对照组及观察组,每组50例。对照组采用咪达唑仑复合阿芬太尼进行麻醉,观察组采用苯磺酸瑞马唑仑复合阿芬太尼进行麻醉。比较两组患者的术中镇静成功率,检查时间、恢复时间、术中输注液体量,术中和术后不良事件发生率。结果观察组的术中镇静成功率为98.00%(49/50),与对照组的96.00%(48/50)比较无明显差异(χ^(2)=0.3436,P=0.5577>0.05)。观察组患者的恢复时间(3.99±0.34)min短于对照组的(4.34±0.38)min,存在统计学意义(P<0.05)。观察组的检查时间短于对照组、术中输注液体量少于对照组,但比较无明显差异(P>0.05)。观察组术中和术后不良事件发生率分别为2.00%、2.00%,低于对照组的16.00%、20.00%,存在统计学意义(P<0.05)。结论老年患者无痛可弯曲支气管镜诊疗中采用苯磺酸瑞马唑仑复合阿芬太尼的临床麻醉效果较好,有利于降低患者不良事件发生率,值得推广。
Objective To evaluate the anaesthesia effect of remimazolam besylate combined with alfentanil in painless and flexible bronchoscopy in elderly patients.Methods A total of 100 elderly patients receiving painless and flexible bronchoscopy were divided into a control group and an observation group according to random number table method,with 50 cases in each group.The control group was anesthetized with midazolam and alfentanil,and the observation group was anesthetized with remimazolam besylateand alfentanil.The success rate of intraoperative sedation,examination time,recovery time,intraoperative fluid infusion,and incidence of intraoperative and postoperative adverse events were compared between the two groups.Results The success rate of intraoperative sedation in the observation group was 98.00%(49/50),and there was no significant difference when compared with 96.00%(48/50)in the control group(χ^(2)=0.3436,P=0.5577>0.05).The recovery time of(3.99±0.34)min in the observation group was shorter than(4.34±0.38)min in the control group,and there was statistical significance(P<0.05).The examination time of the observation group was shorter than that of the control group,and the intraoperative fluid infusion was less than that of the control group,but there was no significant difference(P>0.05).The incidence of intraoperative and postoperative adverse events in the observation group were 2.00%and 2.00%,which was lower than 16.00%and 20.00%in the control group,and there was statistical significance(P<0.05).Conclusion Remimazolam besylate combined with alfentanil has good clinical anesthesia effect in painless and flexible bronchoscopy in elderly patients,which is conducive to reducing the incidence of adverse events in patients,and is worthy of promotion.
作者
赵成龙
赵瑞雪
刘恒明
陈萃
ZHAO Cheng-long;ZHAO Rui-xue;LIU Heng-ming(Department of Anesthesiology,Chiping District People's Hospital,Liaocheng 252100,China)
出处
《中国实用医药》
2024年第18期134-137,共4页
China Practical Medicine
关键词
苯磺酸瑞马唑仑
阿芬太尼
老年患者
无痛可弯曲支气管镜
诊疗
Remimazolam besylate
Alfentanil
Elderly patients
Painless and flexible bronchoscopy
Diagnosis and treatment
