摘要
There were signi cant differences in energy metabolism between normal and tumor cells(normal cells depend on mitochondrial respiration for energy supply,while tumor cells rely on aerobic glycolysis)^([1,2]).Based on this difference,this study aims to provide a new therapeutic strategy for precise radiation protection of normal cells through utilizing selective autophagy induced by MitoQ-constructed pseudo-mitochondrial membrane potential(PMMP)by targeting mitochondrial respiration.Normal cells HA.
基金
Fellow of Youth Innovation Promotion Association(2020414)
Key Program of Natural Science Foundation of Gansu Province(21JR7RA097)。