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骨盆骨折致后尿道闭锁的术式选择及应用

Transperineal surgery for pelvic fracture-induced posterior urethral atresia:Selection and application of surgical modality
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摘要 目的:探讨经会阴治疗骨盆骨折致后尿道闭锁的术式选择以及疗效。方法:2012年1月至2021年12月,116例骨盆骨折导致后尿道断裂或闭锁患者在我院接受治疗。其中79例首选经会阴尿道狭窄切除端端吻合术,对于闭锁段>3 cm,预估尿道对合张力明显者,则切开阴茎中隔,分离切除附着于耻骨下缘的肌键及瘢痕组织,用4-0可吸收线吻合8针。另37例针对近端尿道瘢痕化明显,保留尿道<5 mm且尿道黏膜不完整,不能保证黏膜-黏膜有效缝合的患者,选择行传统尿道拖入术。结果:术后随访3~24个月,手术总体成功率78.4%(91/116),其中尿道端端吻合77.2%(61/79),尿道拖入81.1%(30/37)。排尿不畅18例(15.5%),其中尿道端端吻合13例,占比16.5%(13/79),尿道拖入5例,占比13.5%(5/37)。手术失败7例(6.1%),其中尿道端端吻合5例,占比6.3%(5/79),尿道拖入2例,占比5.4%(2/37)。尿道端端吻合手术后排尿不畅,原因主要为瘢痕切除不彻底导致再次狭窄,以及吻合段两侧尿道不在同轴水平。尿道拖入排尿不畅,分析原因为套入尿道黏膜瓣膜形成,再次瘢痕化导致狭窄或套入尿道不在同轴水平。手术失败7例尿道再次闭锁,1例拒绝再次手术而选择膀胱造瘘管引流,其余6例半年后再次行端端吻合术。结论:对于后尿道闭锁患者,经会阴尿道端端吻合为首选治疗方案;针对掌握后尿道吻合技术早期或每年收治病例较少的医院,尿道拖入术是一种有效治疗方法。 Objective:To investigate the selection of the modality of transperineal surgery and its effect in the treatment of pelvic fracture-induced posterior urethral atresia(PUA).Methods:This study included 116 cases of PUA caused by pelvic fractures treated in our hospital from January 2012 to December 2021.We used transperineal resection of the urethral stricture and end-to-end urethral anastomosis(EEUA)as the first choice in the treatment of 79 cases.For the patients with the urethral atresia segment longer than 3 cm and evident urethral involution tension,we incised the penile septum,separated and removed the muscle tendon and scar tissue attached to the lower border of the pubis,and anastomosed with 4-0 absorbable thread for 8 stitches.For the other 37 cases for which we were not sure of effective suture of the membrane due to obvious scarring of the proximal urethra,the remaining urethra shorter than 5 mm or incomplete urethral mucosa,we selected conventional urethral pull-through operation(UPTO).We followed up the patients for 3-24 months postoperatively.Results:The total success rate of surgery was 78.4%(91/116),81.1%(30/37)in the UPTO and 77.2%(61/79)in the EEUA group,significantly higher in the former than in the latter(P=0.05).The rate of postoperative dysuria was remarkably lower in the UPTO than in the EEUA group(13.5%[5/37]vs 16.5%[13/79],P=0.05),and so was that of surgical failure(5.4%[2/37]vs 6.3%[5/79],P=0.05).The main causes of postoperative dysuria in the EEUA group included restenosis resulting from incomplete scar resection and the two sides of the anastomosed urethral segment not being at the coaxial level,while those in the UPTO group included the formation of mucosal flaps in the pulled-through urethra,and re-scarring leading to stricture or the pulled-through urethra not being at the coaxial level.Among the 7 cases of surgical failure due to recurrence,1 refused reoperation and opted for cystostomy tube drainage,and the other 6 underwent EEUA again 6 months later.Conclusion:EEUA is preferred as t
作者 南玉奎 郭兰戈 姚礼忠 贾宏亮 李九智 NAN Yu-kui;GUO Lan-ge;YAO Li-zhong;JIA Hong-liang;LI Jiu-zhi(Center of Urology,People's Hospital of Xinjiang Uygur Autonomous Region,Urumqi,Xinjiang 830001,China)
出处 《中华男科学杂志》 CAS CSCD 2024年第8期730-733,共4页 National Journal of Andrology
关键词 骨盆骨折 后尿道闭锁 尿道端端吻合术 尿道拖入术 pelvic fracture posterior urethral atresia end-to-end urethral anastomosis urethral pull-through operation
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