摘要
目的:观察疮愈膏外敷对湿热蕴结证肛周脓肿术后创面愈合的促进作用。方法:将70例湿热蕴结证肛周脓肿患者按随机数字表法分为治疗组和对照组,每组35例。在术后常规换药基础上,治疗组给予疮愈膏外敷创面治疗,对照组则给予凡士林纱条外敷创面治疗。比较2组临床疗效、创面愈合时间、疼痛评分、创面分泌物评分、肛门功能指标及血清炎症指标水平。结果:治疗2周后,治疗组临床疗效优于对照组,差异有统计学意义(P<0.05)。治疗组创面愈合时间短于对照组,差异有统计学意义(P<0.05)。治疗2周后,2组疼痛、创面分泌物评分均较术后第2天降低,治疗组疼痛、创面分泌物评分均低于对照组,差异均有统计学意义(P<0.05)。治疗2周后,2组肛管静息压、肛管最大收缩压均较术前降低,治疗组肛管静息压、肛管最大收缩压均低于对照组,差异均有统计学意义(P<0.05)。治疗2周后,2组血清C-反应蛋白(CRP)、白细胞介素-6 (IL-6)及肿瘤坏死因子-α (TNF-α)水平均较术后第2天降低,治疗组血清CRP、IL-6及TNF-α水平均低于对照组,差异均有统计学意义(P<0.05)。结论:疮愈膏外敷可有效改善肛周脓肿湿热蕴结证术后患者的临床症状,降低炎症指标水平,改善肛门功能,促进创面愈合。
Objective:To observe the promotion effect of external application with Chuangyu Ointment on wound healing in postoperative with perianal abscess with damp-heat accumulation syndrome.Methods:A total of 70 cases of patients with perianal abscess with damp-heat accumulation syndrome were divided into the treatment group and the control group according to the random number table method,with 35 cases in each group.On the basis of routine dressing changes after surgery,the treatment group received external application with Chuangyu Ointment on the wound,and the control group received external application with Vaseline gauze on the wound.Compared the clinical effect,wound healing time,pain scores,wound secretion scores,anal function,and serum inflammatory index levels between the two groups.Results:After two weeks of treatment,the clinical effect in the treatment group was better than that in the control group,the difference being significant(P<0.05).The wound healing time in the treatment group was shorter than that in the control group,the difference being significant(P<0.05).After two weeks of treatment,the scores of pain and wound secretion in both groups were decreased when compared to those on the second day after surgery,and the scores of pain and wound secretion in the treatment group were lower than those in the control group,differences being significant(P<0.05).After two weeks of treatment,the resting pressure and maximum systolic pressure of the anal canal in both groups were decreased when compared to those before surgery,and the resting pressure and maximum systolic pressure of the anal canal in the treatment group were lower than those in the control group,differences being significant(P<0.05).After two weeks of treatment,the levels of serum C-reactive protein(CRP),interleukin-6(IL-6),and tumor necrosis factor-α(TNF-α)in the two groups were decreased when compared to those on the second day after surgery,and the levels of CRP,IL-6,and TNF-αin serum in the treatment group were lower than those in the co
作者
张新春
刘佃温
杨会举
刘红敏
ZHANG Xinchun;LIU Dianwen;YANG Huiju;LIU Hongmin(Third Affiliated Hospital of Henan University of Traditional Chinese Medicine,Zhengzhou Henan 450000,China)
出处
《新中医》
CAS
2024年第18期88-92,共5页
New Chinese Medicine
基金
河南省中医药科学研究专项课题(2023ZY2116,20-21ZY2076)
河南省第二批中医药青苗人才培养项目(豫卫中医函[2021]16号)。
关键词
肛周脓肿
湿热蕴结证
疮愈膏
外敷
炎症指标
创面愈合
肛门功能
Perianal abscess
Damp-heat accumulation syndrome
Chuangyu Ointment
External application
Inflammatory index
Wound healing
Anal function
