摘要
目的:探讨甲状腺结节(TN)患者中医证型分布特点及多层螺旋计算机体层成像(MSCT)灌注成像参数的鉴别价值。方法:选取2021年1月~2022年12月本院收治的TN患者130例,均行CT平扫和MSCT灌注扫描,依据中医症候分型标准进行分型。分析TN患者中医证型构成比;比较不同中医证型TN患者的分布特点;比较不同中医证型TN患者血流量(BF)、血容量(BV)、表面通透性(PS)和平均通过时间(MTT)等MSCT灌注参数。结果:130例TN患者中,痰瘀血结证35例(26.92%),气郁痰阻证42例(32.31%),肝火旺盛证33例(25.39%),心肝阴虚证20例(15.38%)。痰瘀血结证患者年龄最大,气郁痰阻证患者BMI最大,常为多发结节且边界不清,肝火旺盛证患者结节病灶组织中常有点状钙化,差异均有统计学意义(P<0.05)。气郁痰阻证TN患者PS最低,心肝阴虚证TN患者MTT最长,肝火旺盛证TN患者BF最高,差异均有统计学意义(P<0.05)。结论:不同中医分型TN患者在年龄、BMI、结节数目、结节边界和钙化情况等方面分布不一,MSCT灌注成像参数可作为中医证型鉴别的客观指标。
Objective To explore the distribution characteristics of TCM syndromes and the differential value of multi-slice spiral computed tomography(MSCT)perfusion imaging parameters in patients with thyroid nodule(TN).Methods A total of 130 patients with TN admitted to the hospital were enrolled between January 2021 and December 2022.All underwent CT plain scan and MSCT perfusion scan.TCM syndromes were classified according to the classification criteria.The composition ratios of TCM syndromes in TN patients were analyzed.The distribution characteristics and MSCT perfusion parameters[blood flow(BF),blood volume(BV),permeability surface(PS),mean transit time(MTT)]in TN patients with different TCM syndromes were compared.Results Among the 130 patients with TN,there were 35 cases with phlegm-blood stasis syndrome(26.92%),42 cases with qi-stagnation phlegm obstruction syndrome(32.31%),33 cases with liver fire flourishing syndrome(25.39%)and 20 cases with heart-liver yin deficiency syndrome(15.38%).The age was the oldest in patients with phlegm-blood stasis syndrome.BMI was the highest in patients with qi-stagnation phlegm obstruction syndrome,and most were accompanied with multiple nodules,with unclear boundaries.In patients with liver fire flourishing syndrome,there was punctal calcification in nodular lesion tissues(P<0.05).PS was the lowest in patients with qi-stagnation phlegm obstruction syndrome,MTT was the longest in patients with heart-liver yin deficiency syndrome,and BF was the highest in patients with liver fire flourishing syndrome(P<0.05).Conclusion There are significant differences in age,BMI,number of nodules,nodule boundary and calcification among TN patients with different TCM syndromes.MSCT perfusion imaging parameters can be applied as objective indexes in the differential diagnosis of TCM syndromes.
作者
魏若愚
杜杨
宗耀华
张旭
袁沙沙
WEI Ruoyu;DU Yang;ZONG Yaohua(Department of Endocrinology,diabetes Hospital District,Xingtai Hebei 054000,China)
出处
《四川中医》
2024年第9期95-98,共4页
Journal of Sichuan of Traditional Chinese Medicine
基金
邢台市重点研发计划自筹项目(编号:2020ZC243,自拟中药方联合西药治疗糖尿病泌尿系统并发症临床研究)。
关键词
甲状腺结节
中医证型分布特点
多层螺旋计算机体层成像
灌注成像参数
Thyroid nodule
Distribution characteristic of TCM syndrome
Multi-slice spiral computed tomography
Perfusion imaging parameter
