摘要
目的观察舒芬太尼、右美托咪定加酮咯酸氨丁三醇用于外科术后镇痛的临床效果。方法选取2021年1月-2022年12月我院行外科术的60例患者为研究对象,按照术后镇痛方案不同将其分为对照组(n=30)与研究组(n=30)。对照组给予舒芬太尼、右美托咪定进行术后镇痛,研究组在对照组基础上加用酮咯酸氨丁三醇进行术后镇痛,比较两组术后疼痛评分(VAS)、Ramsay镇静评分、疼痛控制满意度以及不良反应发生率。结果研究组术后30 min及2、6、12、24 h的VAS评分均低于对照组(P<0.05),而两组术后48 h的VAS评分比较,差异无统计学意义(P>0.05);研究组术后30 min及2、6、12、24、48 h的Ramsay镇静评分与对照组比较,差异无统计学意义(P>0.05);研究组疼痛控制满意度为100.00%,高于对照组的86.67%(P<0.05);观察组不良反应发生率为10.00%,与对照组的13.33%比较,差异无统计学意义(P>0.05)。结论舒芬太尼、右美托咪定加酮咯酸氨丁三醇用于外科术后镇痛效果理想,可减轻术后24 h内疼痛度,提高患者疼痛控制满意度,且不增加不良反应发生率。
Objective To observe the clinical effect of sufentanil,dexmedetomidine and ketorolac tromethamine for postoperative analgesia.Methods A total of 60 patients who underwent surgery in our hospital from January 2021 to December 2022 were selected as the research objects.They were divided into control group(n=30)and study group(n=30)according to different postoperative analgesia schemes.The control group was given sufentanil and dexmedetomidine for postoperative analgesia.The study group was given ketorolac tromethamine for postoperative analgesia on the basis of the control group.The postoperative pain score(VAS),Ramsay sedation score,pain control satisfaction and incidence of adverse reactions were compared between the two groups.Results The VAS score of the study group at 30 min,2,6,12 and 24 h after operation was lower than that of the control group(P<0.05),while there was no significant difference in VAS score between the two groups at 48 h after operation(P>0.05).There was no significant difference in Ramsay sedation score between the study group and the control group at 30 min and 2,6,12,24,48 h after operation(P>0.05).The satisfaction rate of pain control in the study group was 100.00%,which was higher than 86.67%in the control group(P<0.05).The incidence of adverse reactions in the observation group was 10.00%,which was compared with 13.33%in the control group,the difference was not statistically significant(P>0.05).Conclusion Sufentanil,dexmedetomidine and ketorolac tromethamine are ideal for postoperative analgesia.They can reduce pain within 24 hours after surgery,improve patient satisfaction with pain control,and do not increase adverse reactions.
作者
刘炜
郭桂英
戴振琦
李文
刘琴兰
彭友龙
LIU Wei;GUO Gui-ying;DAI Zhen-qi;LI Wen;LIU Qin-lan;PENG You-long(Department of Clinical Pharmacy,Taihe County People's Hospital,Taihe 343700,Jiangxi,China)
出处
《医学信息》
2024年第18期136-138,142,共4页
Journal of Medical Information
基金
2023年度吉安市指导性科技计划项目(编号:20233-043988)。
关键词
舒芬太尼
右美托咪定
酮咯酸氨丁三醇
术后镇痛
Sufentanil
Dexmedetomidine
Ketorolac tromethamine
Postoperative analgesia
