摘要
In the present study,17 flavonoids,including 9 prenylated isoflavones,4 isoflavones,3 flavanones and 1 flavone,were isolated from the twigs and leaves of Erythrina variegata.By NMR spectroscopic means and comparision with the data in the leteratures,their structures were elucidated to be euchrenone b10(1),senegalensin(2),erythrinin C(3),scandenone(4),osajin(5),alpinum isoflavone(6),isoerysenegalensein E(7),erysenegalensein E(8),diprenylgenistein(9),abyssinone V(10),abyssinone V 4′-methyl ether(11),4′,7-dihydroxyflavanone(12),3′,5,7-trihydroxy-4′-methoxyisoflavone(13),2′,4′,5,7-tetrahydroxyisoflavone(14),genistein(15),daidzein(16),and apigenin(17).Except for compounds 1,4-7,and 9-10,other compounds were isolated from E.variegata for the first time.
本研究采用硅胶柱色谱,凝胶Sephadex LH-20柱色谱和反相MCI柱色谱技术对刺桐Erythrina variegata的乙醇提取物进行化学成分的分离纯化,得到17个黄酮类化合物,包括9个异戊烯基取代的异黄酮、4个简单的异黄酮、3个二氢黄酮和1个黄酮。通过核磁共振波谱数据分析和文献对照,将它们的结构鉴定为:euchrenone b10(1),senegalensin(2),erythrinin C(3),scandenone(4),osajin(5),alpinumisoflavone(6),isoerysenegalensein E(7),erysenegalensein E(8),diprenylgenistein(9),abyssinone V(10),abyssinone V 4′-methyl ether(11),4′,7-二羟基二氢黄酮(12),红车轴草素(13),2′,4′,5,7-四羟基异黄酮(14),染料木素(15),黄豆苷元(16)和芹菜素(17)。除化合物1,4-7,9-10外,其余化合物均首次从刺桐中分离得到。
基金
National Natural Science Foundation of China(Grant No.32060099).
