摘要
目的探索中西药联合使用在异位妊娠中的应用效果。方法选取2022年4月至2024年4月于遵义市播州区中医院就诊的70例行保守治疗的异位妊娠患者为研究对象,根据抽签分组法分为西药组和中西药联合组,每组各35例。西药组给予甲氨蝶呤联合米非司酮片进行治疗,中西药联合组在此基础上,给予“宫外孕1号方”口服和“消癥散”贴敷。对比两组异位妊娠患者治疗前后相关指标、临床疗效及不良反应。结果治疗前,西药组和中西药联合组β-人绒毛膜促性腺激素(β-Human Chorionic Gonadotropin,β-HCG)、妊娠囊直径均无显著差异(P>0.05);治疗后,两组异位妊娠患者β-HCG、妊娠囊直径较治疗前均降低(P<0.05),且中西药联合组β-HCG、妊娠囊直径显著低于西药组(P<0.05)。中西药联合组临床有效率为94.49%,显著高于西药组的77.14%(P<0.05)。中西药联合组和西药组治疗期间恶心呕吐、腹泻或便秘、口腔溃疡、白细胞减少、肝损伤的发生率均无显著差异(P>0.05)。结论中西药联合治疗异位妊娠可缩短治疗时间、促进生理功能恢复,临床疗效确切,安全性高。
Objective To explore the application effectiveness of combined traditional Chinese and Western medicine in the treatment of ectopic pregnancy.Methods 70 ectopic pregnancy patients undergoing conservative treatment at Bozhou District Hospital of Traditional Chinese Medicine,Zunyi City,from April 2022 to April 2024 were selected for this study.Using random drawing method,patients were divided into the Western medicine group and the combined traditional Chinese and Western medicine group.The Western medicine group received methotrexate combined with mifepristone.The combined group additionally received oral“Ectopic Pregnancy Formula No.1”and topical application of“Xiaozheng San”.Clinical outcomes,adverse reactions,and relevant indicators before and after treatment were compared between the two groups.Results Prior to treatment,there were no significant dif-ferences inβ-HCG levels and gestational sac diameter between the Western medicine group and the combined group(P>0.05).After treatment,both groups showed reductions inβ-HCG levels and gestational sac diameter(P<0.05),while the combined group demonstrated significantly lower levels compared to the Western medicine group(P<0.05).The clinical efficacy rate in the combined group was 94.49%,significantly higher than that(77.14%)in the Western medicine group(P<0.05).There were no significant differences in the occurrence rates of nausea,vomiting,diarrhea or constipation,oral ulcers,leukopenia,and liver damage between the combined group and the Western medicine group during treatment(P>0.05).Conclusion Combined traditional Chinese and Western medicine therapy for ectopic pregnancy can shorten treatment duration,promote physiological recovery,and achieve precise clinical efficacy with high safety.
作者
肖丹丹
李琼
XIAO Dandan;LI Qiong(Bozhou District Hospital of Traditional Chinese Medicine,Zunyi 563100,China)
出处
《中华灾害救援医学》
2024年第7期836-838,共3页
Chinese Journal of Disaster Medicine
关键词
妊娠
呕吐
腹泻
便秘
口腔溃疡
pregnancy
vomiting
diarrhea
constipation
oral ulcer
