摘要
目的分析了解近年来南宁市华支睾吸虫感染情况变化,为相关部门科学防控华支睾吸虫病提供依据。方法选取2020—2023年广西医大睿谷医学检验有限公司检验科的10554份体检人群样本为研究对象,使用酶联免疫吸附测定法(Enzyme-linked Immunosorbent Assay,ELISA)对华支睾吸虫免疫球蛋白G(Immuno⁃globulin,IgG)抗体水平进行检测分析,并对年份、性别、年龄段、季节、民族、饮食习惯等特征人群组间感染率进行分析。结果10554例体检人群样本中,华支睾吸虫总感染率为28.20%(2976/10554)。不同年份的华支睾吸虫感染率比较,差异有统计学意义(P<0.05);各年份不同性别、年龄段的华支睾吸虫感染率比较,差异有统计学意义(P均<0.05);不同季节、民族、饮食习惯的华支睾吸虫感染率比较,差异有统计学意义(P均<0.05)。结论2020—2023年度南宁市华支睾吸虫感染率总体呈持续下降态势,但仍处于较高水平,季节性和人群差异明显,饮食习惯是关键因素,需加强防控教育,降低感染,且血清检测IgG可作为华支睾吸虫感染的辅助诊断手段。
Objective To analyze and understand the changes of Clonorchis sinensis infection in Nanning City in recent years,so as to provide basis for scientific prevention and control of Clonorchis sinensis in relevant departments.Methods A total of 10554 samples of physical examination population from the laboratory department of Guangxi Medical University Ruigu Medical laboratory Co.,Ltd.from 2020 to 2023 were selected as the research objects.Enzyme-linked immunosorbent assay(ELISA)was used to detect and analyze the Immunoglobulin G(IgG)antibody level of Clonorchis sinensis,and the infection rate among the groups with characteristics such as year,gender,age group,season,nationality,and food habit was analyzed.Results The total infection rate of Clonorchis sinensis was 28.20%(2976/105454)in 10554 samples of physical examination population.There was significant difference in the infection rate of Clonorchis sinensis in different years(P<0.05).There were significant differences in the infection rate of Clonorchis sinensis among different genders and age groups in each year(both P<0.05).There were statistically significant differences in the infection rate of Clonorchis sinensis among different seasons,nationalities,and food habit(all P<0.05).Conclusion The infection rate of Clonorchis sinensis in Nanning City from 2020 to 2023 showed a continuous downward trend,but it was still at a high level.Seasonal and population differences were obvious,dietary habits were the key factors.It was necessary to strengthen prevention and control education to reduce infection,and serum IgG detection could be used as an auxiliary diagnostic method for Clonorchis sinensis infection.
作者
何思倩
梁丽荣
黎乃华
陈虹霖
李碧奇
HE Siqian;LIANG Lirong;LI Naihua;CHEN Honglin;LI Biqi(Department of Laboratory,Guangxi Medical University Ruigu Medical Laboratory Co.,Ltd.,Nanning 530000,Guangxi Zhuang Autonomous Region,China;Department of Pathology the Second Affiliated Hospital of Guangxi Medical University,Nanning 530000,Guangxi Zhuang Autonomous Region,China)
出处
《中国卫生产业》
2024年第9期220-223,共4页
China Health Industry
关键词
华支睾吸虫
流行病学
免疫球蛋白抗体
Clonorchis sinensis
Epidemiology
Immunoglobulin G antibody