摘要
目的探讨加用疏血通治疗急性脑梗死患者的临床效果。方法采用完全随机对照设计,从惠东县多祝镇增光卫生院2022年9月至2023年4月收入的急性脑梗死患者中随机抽取86例,按照随机数字表法分为两组,各43例。对照组:男20例,年龄(60.63±2.39)岁;女23例,年龄(63.16±1.38)岁;采用常规治疗。疏血通组:男21例,年龄(58.08±2.35)岁;女22例,年龄(63.72±2.87)岁;在常规治疗基础上加用疏血通(静脉滴注,每日6 ml,加于250 ml生理盐水中缓慢滴入),7 d为1个疗程,共2个疗程。评估两组治疗后总有效率、满意率、不良反应率及体征指标、健康状况调查简表(SF-36)和中医症候指标评分。统计学方法采用秩和检验、χ^(2)检验和t检验。结果治疗后,疏血通组总有效率、治疗总满意率均高于对照组[95.35%(41/43)比81.40%(35/43)、97.67%(42/43)比79.07%(34/43)],差异均有统计学意义(χ^(2)=4.07、7.24,均P<0.05)。对照组不良反应发生率高于疏血通组[27.91%(12/43)比9.30%(4/43)],差异有统计学意义(χ^(2)=4.91,P<0.05)。两组治疗前体征指标、SF-36、中医证候指标评分差异均无统计学意义(均P>0.05);治疗后,疏血通组均优于对照组(均P<0.05)。结论对急性脑梗死患者采用常规治疗方法加用疏血通治疗,临床疗效好,治疗满意率和有效率高,可推广。
Objective To study the clinical effect of Shuxuetong injection in the treatment of patients with acute cerebral infarction.Methods Eighty-six patients with acute cerebral infarction treated at Zengguang Health Center from September 2022 to April 2023 were selected for the randomized controlled trial,and were divided into a control group and a Shuxuetong group by the random number table method,with 43 cases in each group.There were 20 males who were(60.63±2.39)years old and 23 females who were(63.16±1.38)years old in the control group.There were 21 males who were(58.08±2.35)years old and 22 females who were(63.72±2.87)years old in the Shuxuetong group.Both groups took routine treatment;in addition,the Shuxuetong group intravenously dripped 6 ml Shuxuetong added into 250 ml normal saline.Seven days were one treatment course,and both groups were treated 2 courses.The total effective rates,satisfaction rates,incidences of adverse reactions,physical signs,and scores of the Mos 36-Item Short Form Health Survey(SF-36)and traditional Chinese medicine symptoms were compared between the two groups by the rank sum test,χ^(2) test,and t test.Results After the treatment,the total effective rate and comprehensive treatment satisfaction rate in the Shuxuetong group were higher than those in the control group[95.35%(41/43)vs.81.40%(35/43)and 97.67%(42/43)vs.79.07%(34/43)],with statistical differences(χ^(2)=4.07 and 7.24;both P<0.05).The incidence of adverse reactions in the control group was higher than that in the control group[27.91%(12/43)vs.9.30%(4/43)],with a statistical difference(χ^(2)=4.91;P<0.05).Before the treatment,there were no statistical differences in the physical signs and the scores of SF-36 and traditional Chinese medicine symptoms between the two groups(all P>0.05);after the treatment,the physical signs and the scores of SF-36 and traditional Chinese medicine symptoms in the Shuxuetong group were better than those in the control group(P<0.05).Conclusion Routine treatment combined with Shuxuetong for pat
作者
曹运红
曾武成
杜进林
Cao Yunhong;Zeng Wucheng;Du Jinlin(Department of Internal Medicine,Zengguang Health Center,Duozhu Town,Huidong County,Huizhou 516000,China;Department of Epidemiology and Statistics,School of Public Health,Guangdong Medical University,Dongguan 523808,China)
出处
《国际医药卫生导报》
2024年第17期2936-2941,共6页
International Medicine and Health Guidance News
基金
广东省教育科学“十三五”规划2019年度高校哲学社会科学专项研究(2019GXJK226)。
关键词
急性脑梗死
临床效果
疏血通
Acute cerebral infarction
Clinical effect
Shuxuetong
