摘要
《神农本草经》记载干地黄“逐血痹”,芍药“除血痹”,吴茱萸“除湿血痹”,厚朴主“气血痹”。血痹之病,病在血分,病机为痹,本质为不通。本文以“血痹”为视角解析上述4味治疗血痹的药物(简称“血痹四药”),并梳理其在《伤寒杂病论》中的应用,发现干地黄凉血逐瘀通痹,可治内伤久病血痹、妇产血痹及外伤所致血痹;白芍破阴调营通痹,除营分邪气,可治疗营气、营阴痹结所致血痹;吴茱萸散寒除湿通痹,可治肝家寒凝湿滞所致湿血痹;厚朴燮理阳明气血,可治阳明气血痹。秉承医药圆融理念,本文深化对“血痹”认识,拓展《神农本草经》“血痹四药”的实践价值及临床应用,以期持续丰富因痹致痿病机及通痹治痿法方药和理论内涵。
Shennong′s Classic of Materia Medica(Shen Nong Ben Cao Jing)records that dried Rehmanniae Radix“expels blood impediment”,Paeoniae Radix Alba“eliminates blood impediment”,Euodiae Fructus“dispels dampness and blood impediment”,and Magnoliae Officinalis Cortex treats“qi and blood impediment”.The condition of blood impediment involves the blood aspect,with the pathogenesis being impediment,and the essence of the condition being obstruction.This article analyzed the four drugs used to treat blood impediment,referred to as the“four drugs for treating blood impediment”,and reviewed their applications in the Treatise on Cold Damage and Miscellaneous Diseases(Shang Han Za Bing Lun).It is found that dried Rehmanniae Radix cools the blood,dispels stasis,and unblocks impediments,making it suitable for treating chronic internal injury-induced blood impediment,blood impediment in women related to childbirth,and blood impediment caused by external trauma.Paeoniae Radix Alba breaks yin,regulates the nutrient aspect,and unblocks impediments,removing pathogenic factors from the nutrient aspect,and is used for blood impediment caused by blockages in the nutrient qi and yin.Euodiae Fructus disperses cold,eliminates dampness,and unblocks impediments,and is effective for treating dampness-blood impediment caused by cold coagulation and dampness stagnation in the liver.Magnoliae Officinalis Cortex harmonizes Yangming qi and blood,treating qi and blood impediment in the Yangming meridian.Adhering to the concept of integrating medicine and pharmacology,this article deepened the understanding of“blood impediment”,expanded the practical value and clinical application of the“four drugs for treating blood impediment”as recorded in the Shennong′s Classic of Materia Medica,and aimed to continually enrich the pathogenesis of impediment-induced atrophy-flaccidity disease and the therapeutic methods,formulas,and theoretical concepts for unblocking impediments to treat atrophy.
作者
陈文康
邹和德
赵家有
CHEN Wenkang;ZOU Hede;ZHAO Jiayou(Graduate School of China Academy of Chinese Medical Sciences,Beijing 100700,China)
出处
《世界中医药》
CAS
北大核心
2024年第16期2455-2458,2463,共5页
World Chinese Medicine
基金
国家自然科学基金项目(82274337)——基于肠道菌群-雄激素研究化湿通痹方治疗去势大鼠勃起功能障碍的作用机制
首都卫生发展科研专项(首发2022-2-4271)——化湿通痹方治疗湿热蕴脾型勃起功能障碍的临床研究
中国中医科学院科技创新工程-重大攻关项目(CI2021A02207)——基于AR/VEGF/NO/cGMP通路研究化湿通痹方治疗勃起功能障碍大鼠的疗效机制
北京市中医药科技发展资金项目(QN-2020-29)——基于“因痹致痿”病机对《神农本草经》所载治疗“痹”和“痿”中药梳理研究。
关键词
血痹
干地黄
白芍
吴茱萸
厚朴
《神农本草经》
《伤寒杂病论》
学术探讨
Blood impediment
Dried Rehmanniae Radix
Paeoniae Radix Alba
Euodiae Fructus
Magnoliae Officinalis Cortex
Shennong′s Classic of Materia Medica
Treatise on Cold Damage and Miscellaneous Diseases
Academic exploration
