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冠脉慢性完全闭塞患者冠状动脉侧支循环生成的相关影响因素分析

Analysis of influencing factors related to coronary collateral circulation generation in patients with chronic total occlusion
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摘要 目的:分析冠脉慢性完全闭塞(CTO)患者冠状动脉侧支循环(CCC)生成的状况,分析CCC生成的相关影响因素。方法:回顾性分析CTO患者的临床资料110例,分为无CCC生成组与CCC生成组。记录两组一般资料,采用logistic回归分析影响CTO患者CCC生成的影响因素。结果:110例患者中29例无CCC生成,81例有CCC生成;无CCC生成组有吸烟史、合并糖尿病占比及C反应蛋白(CRP)、促甲状腺激素(TSH)水平高于CCC生成组;游离三碘甲状腺原氨酸(FT3)水平低于CCC生成组(P<0.05)。经logistic回归分析显示,有吸烟史、合并糖尿病、CRP、TSH水平均为CTO患者CCC生成的危险因素(OR>1,P<0.05);FT3水平为CTO患者CCC生成的保护因素(OR<1,P<0.05)。结论:CTO患者CCC生成状况受吸烟史、糖尿病史、CRP、TSH、FY3水平的影响,建议临床在治疗前可予以相应的干预措施,为术后CCC形成提供良好的条件。 Objective:To analyze the status of coronary collateral circulation(CCC)generation in patients with chronic total occlusion(CTO)and the relevant influencing factors of CCC generation.Methods:The clinical data from 110 CTO patients were retrospectively analyzed and the patients were divided into a no-CCC generation group and a CCC generation group.The general data of the two groups were recorded,and the influencing factors affecting CCC generation in CTO patients were analyzed by logistic regression.Results:There were 29 cases without CCC generation and 81 cases with CCC generation in 110 patients.The proportion of patients with smoking history and complicated by diabetes mellitus and the levels of C-reactive protein(CRP)and thyroid-stimulating hormone(TSH)were higher,and the level of free triiodothyronine(FT3)was lower in the no-CCC generation group than the CCC generation group(P<0.05).Logistic regression analysis showed that a history of smoking,complicated by diabetes,the levels of CRP and TSH were risk factors for CCC generation in CTO patients(OR>1,P<0.05);FT3 levels were protective factors for CCC generation in CTO patients(OR<1,P<0.05).Conclusion:The status of CCC generation in CTO patients is affected by smoking and diabetes history and CRP,TSH and FY3 levels,and it is suggested that corresponding interventions should be taken before treatment to provide favorable conditions for postoperative CCC generation.
作者 武延海 WU Yanhai(Department of Cardiology,the Second People’s Hospital of Xinxiang,Xinxiang 453000,China)
出处 《上海医药》 CAS 2024年第15期40-43,共4页 Shanghai Medical & Pharmaceutical Journal
关键词 冠脉慢性闭塞 冠状动脉侧支循环 影响因素 chronic total occlusion coronary collateral circulation influencing factors
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