摘要
目的探究西药和中成药配伍使用所致的不良反应发生情况。方法选取2022年8月—2023年8月本院收治的配伍使用西药和中成药后产生不良反应的88例患者为研究对象,对不合理配伍、不良反应的症状及原因进行统计分析。结果在西药和中成药配伍使用致不良反应的88例患者中,神经系统损伤者42例,约占47.73%,明显高于其他不良反应类型的占比(P<0.05)。分析不良反应的原因可知,有51例患者因中成药用药剂量过大所致,约占57.95%,明显高于其他因素的占比(P<0.05)。在给药方式方面,有45例患者为注射给药,约占51.14%,较其他方式的占比明显偏高(P<0.05)。结论西药和中成药配伍致不良反应以神经系统损害为最多,临床应重视药物配伍的合理性,方可在保证疗效的同时避免不良反应的发生。
Objective To explore incidence of adverse reactions caused by compatibility of western medicine and traditional Chinese patent medicines and simple preparations.Methods The paper chose 88 patients with adverse reactions caused by the combination of western medicine and traditional Chinese patent medicines and simple preparations from August 2022 to August 2023 as study subjects.Symptoms and causes of unreasonable compatibility and adverse reactions were statistically analyzed.Results:Among 88 cases of ADR caused by the combination of western medicine and traditional Chinese patent medicines and simple preparations,42 cases(47.73%)suffered from nervous system injury,significantly higher than other types of adverse reactions(P<0.05).Causes of adverse reactions analysis showed,51 cases were caused by excessive dosage of traditional Chinese patent medicines and simple preparations,accounting for 57.95%,significantly higher than other factors,(P<0.05).As administration methods,45 cases were administered by injection,accounting for approximately 51.14%,significantly higher than other methods(P<0.05).Conclusion The most ADRs caused by combination of western medicine and traditional Chinese patent medicines and simple preparations are nervous system damage.It is necessary to pay attention to rational use of drug compatibility clinically to ensure effect and avoid incidence of adverse reactions.
作者
邱瑞玉
李青梅
QIU Ruiyu;LI Qingmei(Wuwei City Liangzhou Hospital,Wuwei,Gansu 733000)
出处
《智慧健康》
2024年第18期44-46,共3页
Smart Healthcare
关键词
西药
中成药
配伍
不良反应
Western medicine
Traditional Chinese patent medicines and simple preparations
Compatibility
Adverse reactions
