摘要
中药白及Bletilla striata(Thunb.)Reichb.f.是临床上常用的中药材之一,广泛用于各种出血、疮痈肿毒、皮肤皲裂等,具有很高的药用价值,白及多糖是中药白及的主要有效成分。大量研究发现,白及多糖具有止血、抗炎、抗氧化、黏膜保护和抗肿瘤等多种药理活性。同时,白及多糖还具备优良的生物相容性、生物可降解性、生物粘附性等特性,在生物材料及工业领域被广泛应用。近年来,白及多糖的提取、分离、纯化及结构表征相关研究文献较多。然而,各提取工艺及纯化方法对白及多糖的提取率和结构特征差异较大。综述了白及多糖的提取方法、纯化方法和结构特征研究进展,以期为白及多糖的进一步研究和开发提供帮助。
Bletilla striata(Thunb.)Reichb.f.,a traditional Chinese medicinal herb,has been widely used in clinical practice for treating a variety of conditions,including hemorrhages,ulcers,carbuncles,toxic swellings,and skin fissures,showing significantly medicinal value.Bletilla striata polysaccharides are recognized as the herb s main active components.Extensive research has revealed that Bletilla striata polysaccharides exhibit a range of pharmacological activities,such as hemostasis,anti-inflammation,antioxidant properties,mucosal protection,and anti-tumor effects.Furthermore,Bletilla striata polysaccharides possess excellent biocompatibility,biodegradability,and bioadhesive properties,leading to their widespread application in the fields of biomaterials and industry.In recent years,there has been a considerable amount of research literature on the extraction,separation,purification,and structural characterization of Bletilla striata polysaccharides.However,the extraction processes and purification methods vary significantly in terms of the extraction yield and structural characteristics of Bletilla striata polysaccharides.The advancements in extraction methods,purification techniques,and structural characterization studies of Bletilla striata polysaccharides was summarized,aiming to provide assistance for further research and development.
作者
唐秀胜
方镕泽
吴红梅
高源
陈秀敏
陈华国
TANG Xiu-sheng;FANG Rong-ze;WU Hong-mei;GAO Yuan;CHEN Xiu-min;CHEN Hua-guo(The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine,Guiyang 550000,China;Zunyi Hospital of Traditional Chinese Medicine,Zunyi 563000,China;School of Pharmacy,Guizhou University of Traditional Chinese Medicine,Guiyang 550025,China;Guizhou Provincial Institute of Food Inspection and Testing,Guiyang 550001,China;Key Laboratory for Information System of Mountainous Areas and Protection of Ecological Environment,Guizhou Normal University,Guiyang 550001,China)
出处
《化学试剂》
CAS
2024年第9期41-52,共12页
Chemical Reagents
基金
贵州省科技计划项目(黔科合支撑[2020]4Y075号)
遵义市科技计划项目(遵市科合HZ字[2022]433号)。
关键词
白及
多糖
提取
纯化
结构特征
技术
Bletilla striata(Thunb.)Reichb.f.
polysaccharides
extraction
purification
structure characteristic
technology
