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降阶梯疗法治疗新生儿重症感染性肺炎的效果

Effect of de-escalation therapy in the treatment of severe infectious pneumonia in newborns
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摘要 目的探讨降阶梯疗法治疗新生儿重症感染性肺炎的效果。方法选取2021年3月至2023年3月聊城市东昌府区妇幼保健院收治的80例重症感染性肺炎新生儿为研究对象,按照随机数字表法分为对照组(n=40,常规治疗)与观察组(n=40,降阶梯疗法),比较两组治疗效果。结果相较于对照组,观察组治疗总有效率更高(P<0.05);观察组临床指标(体温恢复时间、肺部啰音消失时间、呼吸平稳时间、住院时间)优于对照组(P<0.05);治疗后,观察组白细胞、C反应蛋白水平低于对照组(P<0.05);两组不良反应总发生率比较,差异无统计学意义(P>0.05)。结论降阶梯疗法治疗新生儿重症感染性肺炎的效果较好,能够加快临床症状恢复,且不会增加不良反应,值得推广。 Objective To explore the effect of de-escalation therapy in the treatment of severe infectious pneumonia in newborns.Methods A total of 80 newborns with severe infectious pneumonia in Liaocheng Dongchangfu District Maternal and Child Health Hospital from March 2021 to March 2023 were selected and divided into control group(n=40,routine treatment)and observation group(n=40,de-escalation therapy)by the random number table method.The treatment effect of the two groups was compared.Results Compared with the control group,the total effective rate in the observation group was higher(P<0.05).The clinical indicators(temperature recovery time,r ales disappearance time,stable breathing time,hospital stay time)in the observation group were better than those in the control group(P<0.05).After treatment,the levels of white blood cell and C-reactive protein in the observation group were lower than those in the control group(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion The effect of de-escalation therapy in the treatment of severe infectious pneumonia in newborns is better,which can accelerate the recovery of clinical symptoms,does not increase adverse reactions,and is worth promoting.
作者 汪静 王凤娟 WANG Jing;WANG Fengjuan(Liaocheng Dongchangfu District Maternal and Child Health Hospital,Shandong Province,Liaocheng 252000,China)
出处 《妇儿健康导刊》 2024年第16期75-78,共4页 JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE
关键词 降阶梯疗法 新生儿重症感染性肺炎 临床症状 De-escalation therapy Severe infectious pneumonia in newborn Clinical symptom
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