摘要
目的探究宫颈环形电切术(LEEP)对保留生育功能宫颈上皮内瘤变(CIN)患者术后宫颈修复、宫颈狭窄及并发症的影响。方法选取2019年1月至2021年1月吉安市中心人民医院收治的72例CIN患者作为研究对象,采用随机数字表法分为A组与B组,每组36例。A组实施冷刀锥切术(CKC)治疗,B组实施LEEP治疗。比较两组手术相关指标、宫颈愈合情况、宫颈狭窄情况及并发症发生率、复发率、残留率。结果B组手术时间短于A组,术中出血量少于A组,锥切组织面积小于A组,锥高低于A组,差异有统计学意义(P<0.05)。两组浅度锥切后宫颈完全愈合率比较差异无统计学意义;B组深度锥切后宫颈完全愈合率高于A组,差异有统计学意义(P<0.05)。两组浅度锥切宫颈狭窄发生率比较差异无统计学意义;B组深度锥切宫颈狭窄发生率、宫颈狭窄总发生率均低于A组,差异有统计学意义(P<0.05)。B组并发症发生率低于A组,差异有统计学意义(P<0.05);两组复发率、残留率比较差异无统计学意义。结论LEEP治疗保留生育功能CIN患者,可提升其宫颈愈合率,降低宫颈狭窄发生率。
Objective To investigate the effects of loop electrosurgical excisional procedure(LEEP)on postoperative cervical repair,cervical stenosis and complications in patients with fertility preserving cervical intraepithelial neoplasia(CIN).Methods 72 patients with CIN admitted to Ji'an Central People's Hospital from January 2019 to January 2021 were selected as the study subjects,they were divided into the group A and the group B accroding to the random number table method,with 36 cases in each group.The group A was treated with cold knife conectomy(CKC),the group B was treated with LEEP.The operative-related indexes,cervical healing,cervical stenosis,complication rate,recurrence rate and residual rate were compared between the two groups.Results The operative time in the group B was shorter than that in the group A,the intraoperative blood loss was less than that in the group A,conical tissue area was smaller than that in the group A,and the conical height was lowerr than that in the group A,and the differences were statistically significant(P<0.05).There was no significant difference in the rate of cervical complete healing after shallow cone resection between the two groups;the rate of complete cervical healing after deep cone resection in the group B was higher than that in the group A,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of cervical stenosis after shallow cone resection between the two groups;the incidence of cervical stenosis and the total incidence of cervical stenosis after deep cone resection in the group B were lower than those in the group A,and the differences were statistically significant(P<0.05).The incidence of complications in the group B was lower than that in the group A,the difference was statistically significant(P<0.05);there was no significant difference in recurrence rate and residual rate between the two groups.Conclusion LEEP treatment for patients with fertility preserving CIN,can improve its cervical healing rate,and re
作者
李星星
王小兵
郭艳琴
LI Xingxing;WANG Xiaobing;GUO Yanqin(Department of Obstetrics and Gynecology,Ji'an Central People's Hospital,Ji'an,Jiangxi,343000,China)
出处
《当代医学》
2024年第13期47-51,共5页
Contemporary Medicine
关键词
宫颈上皮内瘤变
宫颈环形电切术
宫颈狭窄
Cervical intraepithelial neoplasia
Circular electrotomy of cervix
Cervical stenosis