摘要
What is already known on this topic?Exposure to fine particulate matter(PM_(2.5))was linked to endocrine hormone disruption in the reproductive system.Nonetheless,it was unclear which specific components of PM_(2.5) were primarily responsible for these associations.What is added by this report?The study presented the initial epidemiological evidence that brief exposure to PM_(2.5) can elevate estradiol levels in postmenopausal women.Various particle components had unique effects,with watersoluble ions and specific inorganic elements like Ag,As,Cd,Hg,Ni,Sb,Se,Sn,and Tl potentially playing significant roles in increasing estradiol levels.What are the implications for public health practice?The study established that the prevalence of air pollution,along with its specific components,has been recognized as a novel risk factor affecting the balance of sex hormones.
基金
Supported by the National Natural Science Foundation of China(No.82025030,No.81941023)
the National Key Research and Development Program of China(No.2022YFC3702700)
the Open Fund provided by the Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control(KHK 2104).
