摘要
目的:探讨孤立性甲状腺微小乳头状癌微波消融的治疗效果。方法:回顾性分析72例采用微波消融治疗的甲状腺微小乳头状癌患者,在术后即刻超声造影评估消融范围并计算坏死灶的体积,于术后1、3、6、12个月行常规超声检查,观察病灶吸收情况,比较病灶的体积、体积缩小率、甲状腺功能,根据结节最大直径分为直径>5 mm和直径≤5 mm,比较病灶的体积缩小率,观察有无新发病灶及淋巴结转移。结果:术后1、3、6、12个月随访,体积缩小率分别为37.3%、73.5%、91.5%、100.0%,差异有统计学意义(P<0.05);最大直径>5 mm的结节体积缩小率小于结节最大直径≤5 mm组,差异有统计学意义(P<0.05);术后1个月与术前甲状腺功能变化差异无统计学意义(P>0.05),随访1年未发现新发病灶及颈部淋巴结转移。结论:微波消融治疗孤立性甲状腺微小乳头状癌疗效确切,并且体积越小吸收越快。
Objective:To investigate the therapeutic effect of microwave ablation of solitary micropapillary thyroid carcinoma.Methods:A retrospective analysis was performed in 72 patients with micropapillary carcinoma of the thyroid treated by microwave ablation.The ablation range and volume of necrotic lesion were evaluated by contrast-enhanced ultrasound immediately after surgery.Routine ultrasound examination was performed at 1,3,6 and 12 months after operation to observe the absorption of the lesions,and compare the volume,volume reduction rate and thyroid function of the lesions.According to the maximum diameter of nodules,the nodules were divided into diameter >5 mm and diameter ≤5 mm.The volume reduction rate of lesions was compared to observe whether there were new lesions and lymph node metastasis.Results:At 1,3,6 and 12 months follow-up,the volume reduction rates were 37.3%,73.5%,91.5% and 100.0%,respectively,with statistical significance(P<0.05).The size reduction rate of nodules with maximum diameter >5 mm was lower than that of nodules with maximum diameter ≤5 mm,and the difference was statistically significant(P<0.05).There was no statistically significant change in thyroid function between 1 month after surgery and before surgery(P>0.05),and no new lesions or cervical lymph node metastases were found at 1-year follow-up.Conclusion:Microwave ablation is effective in the treatment of solitary micropapillary thyroid carcinoma,and the smaller the size,the faster the absorption.
作者
周玉叶
吕玲
吕顺
巨雅莉
马鹏杰
牛惠萍
ZHOU Yuye;Lü Ling;Lü Shun;JU Yali;MA Pengjie;NIU Huiping(Changzhi Medical College)
出处
《长治医学院学报》
2024年第4期289-292,297,共5页
Journal of Changzhi Medical College
关键词
甲状腺乳头状癌
微波消融
超声介入
papillary thyroid cancer
microwave ablation
ultrasound intervention
