摘要
目的:探讨晋唐时期方药代表著作中治疗消渴的组方用药规律和特点,以期为中医临床诊疗本病提供理论依据及用药参考。方法:检索电子版《中华医典》第五版《肘后备急方》、《小品方》、《刘涓子鬼遗方》、《千金要方》、《千金翼方》、《外台秘要》中涉及的方剂进行整理,应用数据挖掘技术进行分析。结果:收集方药119首涉及药物149味,高频中药(频率≥10%)为甘草、麦门冬、瓜蒌、人参、生地黄等20味;药物种类有补气药、补阴药、清热泻火药等39种;药性以寒为主,药味多偏甘苦;主要归经为肺经、脾经、胃经,其次为心经、肾经;关联规则分析得到药物组合15个;挖掘出3个核心药物聚类。结论:晋唐医家诊疗消渴法宗《内经》,开创三消论治之先河,构建出了目前临床常用证型框架,为后世医家研究拓展该病开辟了广阔道路。
Objective:To explore the prescription and drug composition rules and characteristics of the treatment of diabetes in the representative works of prescriptions and medicines in the Jin and Tang Dynasties,in order to provide theoretical basis and drug reference for the clinical diagnosis and treatment of this disease in traditional Chinese medi-cine.Methods:The prescriptions involved in the electronic version of the fifth edition of“Chinese Medical Classics”“Emergency Prescriptions for the Elbow”,“Xiaopin Prescriptions”,“Gui Yi Prescriptions of Liu Juanzi”,“Qianjin Yaofang”,“Qianjin Yifang”,and“Wai Tai Mi Yao”were retrieved and sorted,and data mining technology was used for analysis.Results:119 prescriptions involving 149 drugs were collected,and 20 high-frequency Chinese medicines(frequency≥10%)were licorice,Ophiopogon Japonicus,Trichosanthes Kirilowii,Ginseng,and Rehmannia Glutinosa.There were 39 types of drugs,including Qi-Tonifying drugs,Yin-Tonifying drugs,and heat-clearing and fire-purging drugs.The drug properties were mainly cold,and the taste was mostly sweet and bitter.The main meridians were lung meridian,spleen meridian,and stomach meridian,followed by heart meridian and kidney meridian.Association rule analysis obtained 15 drug combinations;and 3 core drug clusters were mined.Conclusion:The diagnosis and treatment of diabetes by doctors in Jin and Tang dynasties was based on the Neijing,which pioneered the treatment of the three types of diabetes and constructed a common clinical syndrome framework,which opened up a broad road for later doc-tors to study and expand the disease.
作者
付艺
王翔宇
韦溶锴
宋雪城
周卓宁
FU Yi;WANG Xiangyu;WEI Rongkai;SONG Xuecheng;ZHOU Zhuoning(Guangxi University of Traditional Chinese Medicine,Guangxi Nanning 530000,China;Ruikang Hospital Affiliated of Guangxi University of Traditional Chinese Medicine,Guangxi Nanning 530000,China)
出处
《中医药临床杂志》
2024年第8期1524-1529,共6页
Clinical Journal of Traditional Chinese Medicine
基金
广西中医药适宜技术开发与推广项目(GZSY23-44)
广西中医药大学2022年研究生教育创新计划项目(YCSY2022035)。
关键词
糖尿病
消渴
用药规律
数据挖掘
晋唐时期
Diabetes
Xiao Ke
Medication rules
Data mining
Jin and Tang dynasties
