摘要
目的探讨30%超分子水杨酸联合420nm强脉冲光治疗面部脂溢性皮炎的临床疗效及安全性。方法回顾性纳入2018年1月到2021年12月西南医科大学附属中医医院医学美容中心就诊的面部脂溢性皮炎患者60例,男20例、女40例,年龄18~44(28.0±6.8)岁。分为水杨酸组(30%超分子水杨酸治疗)、强脉冲光组(420nm强脉冲光治疗)、联合治疗组(30%超分子水杨酸联合420nm强脉冲光治疗),每组20例。每2周治疗1次,共4次。每次治疗后收集不良反应,治疗结束后4周评估疗效。结果治疗后,联合治疗组临床症状及体征总评分低于水杨酸组和强脉冲光组[(3.95±1.73)分比(7.15±2.06)、(7.50±1.73)分,F=22.43,P<0.05]。治疗后联合治疗组的临床症状改善有效率为95%(19/20),优于水杨酸组(65%,13/20)和强脉冲光组(60%,12/20)(χ^(2)=7.33,P<0.05)。3组均未见明显不良反应。结论30%超分子水杨酸联合420nm强脉冲光治疗面部脂溢性皮炎安全有效。
Objective To investigate the clinical efficacy of 30%supramolecular salicylic acid combined with 420 nm intense pulsed light in the treatment of facial seborrheic dermatitis.Methods A total of 60 patients with facial seborrheic dermatitis were selected from January 2018 to December 2021,that were randomly divided into 30%salicylic acid group,420 nm intense pulsed light group and combined group.Each group had 2o patients.They were treated once every two weeks in four consecutive rounds.The adverse reactions of patients were followed up each time,and the data were analysed and evaluated four weeks after the last treatment.Results After treatment,the total score of clinical symptoms and signs in the combined group were significantly lower than those in the other groups(3.95±1.731 vs.7.15±2.059,7.50±1.732,F=22.434,P<0.05).The effective rate in combined group was 95%,which was significantly higher than 65%of salicylic acid group and 60%of intense pulsed light group(χ^(2)=7.33,P<0.05),and no obvious adverse reactions were found in the three groups.Conclusions 30%supramolecular salicylic acid combined with 420 nm intense pulsed light is safe and effective in the treatment of facial seborrheic dermatitis.
作者
邓映
杨洪秋
杜晓霜
刘萍
杜宇
Deng Ying;Yang Hongqiu;Du Xiaoshuang;Liu Ping;Du Yu(Medical Cosmetic Center,Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University,Luzhou646000,China)
出处
《中华医学美学美容杂志》
2024年第4期377-381,共5页
Chinese Journal of Medical Aesthetics and Cosmetology
关键词
脂溢性皮炎
面部
超分子水杨酸
强脉冲光
疗效
Seborrheic dermatitis
Face
Supramolecular salicylic acid
Intense pulsed light
Efficacy
